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1.
Gan To Kagaku Ryoho ; 50(13): 1390-1392, 2023 Dec.
Artigo em Japonês | MEDLINE | ID: mdl-38303284

RESUMO

A 63-year-old female patient was diagnosed with cecal cancer(cT3, N2a, M0)and underwent surgery for the first time. Only laparoscopic ileocecal resection(D3 dissection)was performed because intraperitoneal observation revealed peritoneal metastasis around the tumor and uterus. We decided to perform a radical resection because the peritoneal metastasis was localized by FDG-PET/CT. Five courses of neoadjuvant chemotherapy(mFOLFOX6)were performed to shrink the tumor. Unrecognized peritoneal metastases were found in other areas during the second surgery. Although the extent of the peritoneal metastasis was P3, all lesions had been resected. No perioperative complications occurred, and adjuvant chemotherapy was administered to the patient. Recurrence was not observed until 6 months postoperatively.


Assuntos
Neoplasias do Ceco , Laparoscopia , Neoplasias Peritoneais , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias Peritoneais/tratamento farmacológico , Neoplasias Peritoneais/cirurgia , Neoplasias Peritoneais/secundário , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada , Terapia Neoadjuvante , Neoplasias do Ceco/tratamento farmacológico , Neoplasias do Ceco/cirurgia , Neoplasias do Ceco/patologia , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico
2.
Gan To Kagaku Ryoho ; 43(9): 1101-3, 2016 Sep.
Artigo em Japonês | MEDLINE | ID: mdl-27628552

RESUMO

A 52-year-old woman presented with redness and swelling with a peau d'orange appearance in the whole right breast. Ultrasound revealed elevated subcutaneus fat density and a diffuse hypoechoic area. She was diagnosed with inflammatory breast cancer(T4dN2M0, Stage III B of the HER2 subtype). After 4 courses of EC treatment as primary systemic therapy, the hypoechoic area was still present. Subsequent chemotherapy with pertuzumab, trastuzumab, and docetaxel was effective, as hypoechoic area was not observed on ultrasound. She underwent mastectomy and axillary dissection, and pathological examination revealed pCR. At present, 2 years after surgery, the patient is alive with no reccurence.


Assuntos
Anticorpos Monoclonais Humanizados/uso terapêutico , Neoplasias Inflamatórias Mamárias/tratamento farmacológico , Terapia Neoadjuvante , Biópsia , Feminino , Humanos , Neoplasias Inflamatórias Mamárias/química , Neoplasias Inflamatórias Mamárias/patologia , Neoplasias Inflamatórias Mamárias/cirurgia , Mastectomia , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Receptor ErbB-2/análise , Receptor ErbB-2/metabolismo , Resultado do Tratamento
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