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1.
Sci Rep ; 13(1): 23026, 2023 Dec 27.
Artigo em Inglês | MEDLINE | ID: mdl-38155205

RESUMO

Finding the optimal embedding of networks into low-dimensional hyperbolic spaces is a challenge that received considerable interest in recent years, with several different approaches proposed in the literature. In general, these methods take advantage of the exponentially growing volume of the hyperbolic space as a function of the radius from the origin, allowing a (roughly) uniform spatial distribution of the nodes even for scale-free small-world networks, where the connection probability between pairs decays with hyperbolic distance. One of the motivations behind hyperbolic embedding is that optimal placement of the nodes in a hyperbolic space is widely thought to enable efficient navigation on top of the network. According to that, one of the measures that can be used to quantify the quality of different embeddings is given by the fraction of successful greedy paths following a simple navigation protocol based on the hyperbolic coordinates. In the present work, we develop an optimisation scheme for this score in the native disk representation of the hyperbolic space. This optimisation algorithm can be either used as an embedding method alone, or it can be applied to improve this score for embeddings obtained from other methods. According to our tests on synthetic and real networks, the proposed optimisation can considerably enhance the success rate of greedy paths in several cases, improving the given embedding from the point of view of navigability.

2.
Sci Rep ; 13(1): 4226, 2023 03 14.
Artigo em Inglês | MEDLINE | ID: mdl-36918593

RESUMO

In the past few years COVID-19 posed a huge threat to healthcare systems around the world. One of the first waves of the pandemic hit Northern Italy severely resulting in high casualties and in the near breakdown of primary care. Due to these facts, the Covid CXR Hackathon-Artificial Intelligence for Covid-19 prognosis: aiming at accuracy and explainability challenge had been launched at the beginning of February 2022, releasing a new imaging dataset with additional clinical metadata for each accompanying chest X-ray (CXR). In this article we summarize our techniques at correctly diagnosing chest X-ray images collected upon admission for severity of COVID-19 outcome. In addition to X-ray imagery, clinical metadata was provided and the challenge also aimed at creating an explainable model. We created a best-performing, as well as, an explainable model that makes an effort to map clinical metadata to image features whilst predicting the prognosis. We also did many ablation studies in order to identify crucial parts of the models and the predictive power of each feature in the datasets. We conclude that CXRs at admission do not help the predicting power of the metadata significantly by itself and contain mostly information that is also mutually present in the blood samples and other clinical factors collected at admission.


Assuntos
Inteligência Artificial , COVID-19 , Humanos , COVID-19/diagnóstico por imagem , Metadados , Raios X , Hospitalização
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