RESUMO
The clinical in vivo tissue bulks' surface is always coarse and shows a complex microscopic geometry which may affect the visual effect of polarization images and calculation of polarization parameters of the sample. To confirm whether this effect would cause identification difficulties and misjudgments on the target recognition when performed the polarization imaging based on 3 × 3 Mueller matrix measurement, cylindrical type and slope type physical models were used to study and analyze the effect of the surface with complex microscopic geometry on the polarization images. Then, clinical tumor bulk samples were used to interact with different sizes of patterns to simulate the different complex microscopic geometry and test the coarse surface effect on polarization images. Meanwhile, assessment parameters were defined to evaluate and confirm the variation between two polarization images quantitatively. The results showed that the polarization imaging of the sample surface with the complex microscopic geometry led to acceptable visual effect and limited quantitative variation on the value of polarization parameters and assessment parameters, and it caused no identification difficulties on target recognition, indicating that it is feasible to apply the polarization imaging based on 3 × 3 Mueller matrix measurement on clinical in vivo tissues with the complex microscopic geometry sample surface.
RESUMO
OBJECTIVE: By reviewing the medical treatments for aplastic anemia (AA, Suilao Disease), which is the important research interest of Collaborative Group, Key Department of Blood Disease, State Administration of Chinese medicine, the consensus on the diseases have been reached among the different units of the collaborative group. METHODS: Using qualitative analysis, we determined the characteristics, location and pathogenesis of Suilao disease. We discovered the ways of traditional Chinese medical treatment in curing Suilao disease. RESULTS: Acute AA (acute suilao) and chronic AA (chronic suilao) diseases require different treatment. Acute AA requires 3 phrases of treatments, which are "cold", "warm" and "hot". However, chronic AA requires a dialectic treatment, which involves reinforcement of the Shen (Kidney). Suitable Chinese medical treatments for curing Suilao disease were discussed and reached a consensus. CONCLUSION: It is concluded that a summarized therapy approved by many experts could be widely used.
RESUMO
OBJECTIVE: To observe the effect of Busui Shengxue Granule ((see text) Herbal granule for replenishing marrow to produce blood) on chronic aplastic anemia (CAA) patients' integrin alpha 6 (VLA-6/CD49f) and laminin (Ln). METHODS: Sixty-five patients were divided into experimental group and control group through random number table. There were 34 patients, 17 were male and 17 female, aged 2-67, with a medianage of 30.2 +/- 8.6, in the experimental group, including 17 patients of kidney-yin deficiency and 17 of kidney-yang deficiency, treated by Busui Shengxue Granule. There were 31 patients in the control group, 16 were male and 15 female, aged 4-65, with a medianage of 31.2 +/- 8.0; administered Zaizhang Shengxue Tablet (see text) Herbal tablet for chronic aplastic anemia). Both groups were treated for six months and compared with 10 normal persons after the treatment. Flow cytometry was adopted to detect the change in the expression of VLA-6/CD49f, receptor in mononuclear cells of CAA patients and normal persons. Enzyme-linked immunosorbent assay was applied to detect the expression of peripheral serum Ln. RESULTS: CAA patients' VLA-6/CD49f was in the state of low expression and Ln in the state of high expression. After the treatment, both VLA-6/CD49f and Ln were regulated to some extent and the change in the experimental group was better than that of the control group. Compared with the kidney-yin deficiency patients, those indices of kidney-yang deficiency patients were easier to correct. CONCLUSION: The VLA-6/CD49f and Ln expressions of CAA patients are abnormal. The treatment with Busui Shengxue Granule makes both of them improved.
