RESUMO
The aim of the study was to determine the prevalence of selective lactose malabsorption (SLM) in Khants, a small finno-ugric nation living in West Siberia. A total of 80 Khants from the Surgut region (Tyumen territory) were studied. The diagnosis of SLM was based on the evidence obtained at a 50 g lactose and, if possible, a 25 g + 25 g galactose-glucose loads. In 6 cases electron-microscopic examination of the duodenal mucosa was performed. The prevalence of SLM in the Khants reached 93-94% being the highest in CIS.
Assuntos
Intolerância à Lactose/etnologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Feminino , Humanos , Intolerância à Lactose/diagnóstico , Masculino , Prevalência , Federação Russa/epidemiologiaRESUMO
BACKGROUND: We wanted to estimate the prevalence of selective lactose malabsorption (SLM) in Khants, a small Finno-Ugric population living in Western Siberia who have traditionally consumed no milk in adulthood. METHODS: A total of 80 Khants, aged 8-57 years and living on the middle reaches of the River Ob, were studied. The diagnosis was based on a lactose tolerance test; general malabsorption was excluded by a glucose-galactose tolerance test whenever possible. In six subjects electronmicroscopic examination of the duodenal mucosa was performed. RESULTS: The prevalence of SLM in the Khants was 94%. CONCLUSION: This is the highest prevalence found in the previous Soviet Union.
