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Gan To Kagaku Ryoho ; 36(4): 667-70, 2009 Apr.
Artigo em Japonês | MEDLINE | ID: mdl-19381045

RESUMO

A 78-year old man underwent low anterior resection for Stage IIIb rectal cancer(Ra). After surgery, he underwent the Roswell Park Memorial Institute(RPMI)regimen for 6 months followed by oral UFT for 8 months. Since liver metastasis(S6)recurred 2 years and 2 months after surgery, he underwent S6 subsegmentectomy. Four years and 4 months later, he developed multiple lymph node metastases(the Virchow, paraaortic, and intrapelvic lymph nodes), for which FOLFIRI therapy was started, but converted to the RPMI regimen because of strong gastrointestinal side effects. After 3 courses of this regimen, tumor markers returned to normal, and imaging studies showed that the metastases had disappeared. This was interpreted as a complete response(CR). The patient has maintained the complete response for 1 year and 4 months since the start of the RPMI regimen.


Assuntos
Antineoplásicos/uso terapêutico , Fluoruracila/uso terapêutico , Leucovorina/uso terapêutico , Neoplasias Retais/tratamento farmacológico , Neoplasias Retais/patologia , Idoso , Biomarcadores Tumorais/sangue , Humanos , Metástase Linfática/diagnóstico por imagem , Metástase Linfática/patologia , Masculino , Tomografia por Emissão de Pósitrons , Neoplasias Retais/sangue , Neoplasias Retais/cirurgia , Indução de Remissão , Tomografia Computadorizada por Raios X
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