[Structurally functional modifications of the human lymphocytes induced by influence of UV-light].

The influence of UV-light (240-390 nm) in dose 75.5-1510 J/m2 on the structural functional qualities (cytotoxic activity, antibody-produced ability, a level of expression of superficial receptors, a level cAMP) of lymphocytes peripheral blood of donors was investigated. Corregative action of UV-radiation on cytotoxic activity of lymphocytes in relation to cells of Ehrlich ascite carcinoma was revealed. The interrelation of modification types of plasmatic membrane components with a level of functional activity of lymphocytes was established. Was shown, that UV-light induces the decrease in a secondary level of messenger cAMP in cytosol of the photomodified cells. It is revealed, that UV-radiation causes stimulation of antibody-independent mechanism of cytotoxic lymphocytes, which is connected with activation of T-cells and with inhibition of antibody-dependent mechanism of cytotoxic activity.

Effect of helium-neon laser on activity and optical properties of catalase.

The effects of laser (632.8 nm) on functional and spectral properties of catalase at pH 6.0-7.4 were studied. Laser irradiation led to photoactivation of the enzyme at pH 7.1-7.4. Changes in the spectral properties of photomodified hemoprotein were found in the absorption spectrum of the protein component: apoenzyme displayed protective effects in relation to ferroporphyrin. Structural modifications of catalase induced by helium-neon laser irradiation correlated with its functional properties. These results can be used in clinical practice to design the individual management program.

[The dynamic indices of expectoration and of the clinical manifestations during the treatment of bronchial asthma patients using extracorporeal methods]. / Dinamika pokazatelei ékspektoratsii i klinicheskikh proiavlenii pri lechenii bol'nykh bronkhial'noi astmoi s primeneniem ékstrakorporal'nykh metodov.

Positive changes were reported in the course of bacterial asthma due to extracorporeal and quantum therapy. The adjuvant use of plasmapheresis and UV blood irradiation contributed much to expectoration improvement.