[Peculiarities of neuronal sizes of anterior dorsal and reticular nuclei of the thalamus in women].

Profile field areas (PFA) were studied in 100 neurons in the anterior dorsal (ADN) and reticular nuclei (RN) of the thalamus in the left and right cerebral hemispheres of five women (10 hemispheres) aged from 19 to 33 years, using 20 microm-thick sections stained with Nissl's cresyl violet. Morphometric method using Image Scope Color <> program-device complex (Germany) was applied. <> (Wilcoxon matched pairs test) was used for the analysis of the data obtained. Greater variability of neuronal maximal PFA was detected in both nuclei in the right hemisphere. PFA average value was greater in RN than in ADN, and this difference was more significant in the left hemisphere in all women. The variability of average PFA value was greater in RN than in ADN, however in both nuclei it was greater on the right than on the left. Neuronal PFA variability was more expressed than its interhemispheric asymmetry.

[Dynamics of parameters of heart rate variability after radiofrequency ablation in patients with paroxysmal supraventricular tachycardia: holter ECG monitoring data].

Changes of parameters of heart rate variability (HRV) in patients with supraventricular tachycardia (SVT) immediately after radiofrequency ablation (RFA) have been demonstrated earlier. However dynamics of HRV parameters after RFA has not been sufficiently studied. For elucidation of dynamics of HRV parameters in patients with SVT after RFA we conducted analysis of HRV basing on data of 24 hour Holter ECG monitoring before RFA, on day 2, in 1 week and 1 month after intervention in 27 patients with paroxysmal SVT. Statistically significant lowering of temporal (SDNNi, RMSSD, NN50, pNN50) and spectral (VLF, LF, HF) HRV parameters were found on day 2 and in 1 week after RFA compared with data obtained before intervention. In 1 month after RFA the studied parameters of HRV did not differ from baseline values. Reversible changes of HRV parameters evidencing for transitory autonomic dysfunction are observed after RFA.

[Effect of radio frequency catheter ablation on spectral parameters of heart rate variability in patients with paroxysmal supraventricular tachyarrhythmias]. / Vliianie radiochastotnoi kateternoi ablatsii na spektral'nye pokazateli variabel'nosti ritma serdtsa u bol'nykh s paroksizmal'nymi nadzheludochkovymi takhiaritmiiami.

AIM: To assess effect of radio frequency catheter ablation (RFCA) on heart rate variability (HRV) in patients with supraventricular tachyarrhythmias (SVT). METHODS: Spectral analysis of HRV on 5-minute ECG strips was carried out in 19 patients with SVT before and 2 days after RFCA. RESULTS: Both total and high frequency power significantly decreased (p<0,05) after RFCA in supine and orthostatic positions. Significant decrease of low frequency power occurred after RFCA in orthostatic position. CONCLUSION: In patients with SVT RFCA alters autonomic regulation of chronotropic function of the heart. Sympathetic and parasympathetic influences on the chronotropic function of the heart are attenuated in early period after the procedure.

[Radical surgical treatment of atrial flutter]. / Radikalnoe khirurgicheskoe lechenie trepetaniia predserdii.

From January 1983 to May 1992 a total of 40 patients with a tachysystolic type of atrial flutter (AF) refractory to preventive antiarrhythmic therapy were examined and operated on. The obligatory stage of a preoperative examination was invasive phonoelectrocardiography. The effects of "entrainment" and adaptation of refractory periods of various portions of atria were estimated depending on the duration of a basic stimulation cycle. In inducing a AF paroxysm, the site of early A spike appearance was determined and endomyocardial mapping was performed. During intraoperative mapping, the data on low-amplitude and fragmented activity were processed by a computer. The sequence of the electric activation of the atria in AF was also determined. Twenty seven transthoracic operations were performed via extracorporeal circulation, 9 of them underwent laser or cryogenic isolation of the atrioventricular node, 4 laser photo ablation, 10 cryodestruction of arrhythmogenic areas. Resection of 1/3 of the marginal crust, sinoatrial node with subsequent implantation of a pacemaker was made in 1 patient in the AA1 mode. Three patients underwent operation to create a labyrinth by J. Cox and a corridor by J. Quiraudon. The closed heart operations involved both transvenous electrodestruction of arrhythmogenic areas (5 patients) and destruction of the His bundle with developed complete block and pacemaker implantation in the VVI mode (8 patients). The best results of surgical treatment were obtained in young patients with idiopathic AF (Type 1), when the areas of fragmented and low-amplitude activity could be accurately determined.

[The electrophysiological diagnosis and surgical treatment of atrial flutter]. / Elektrofiziologicheskaia diagnostika i khirurgicheskoe lechenie trepetaniia predserdii.

From 1982 to the late 1990 thirty-three patients with tachysystolic atrial fibrillation refractory to preventive antiarrhythmic therapy were examined and operated on. Invasive electrophysiological investigation was a must in the preoperative examination. The "entrainment" and "adaptation" effects of the refractory periods of different parts of the atria were estimated depending on the duration of the basic cycle of pacing. After provoking atrial flutter paroxysm the place of the early appearance of A spike was determined and endocardial mapping was performed. During intraoperative mapping, the data of low-amplitude and fragmented activity were processed by a computer; the sequence of electric activation of the atria was determined on flutter. 20 transthoracic operations with extracorporeal circulation were made. Of these, there were 7 operations of laser or cryogenic isolation of the AB node, 30 of laser photo ablation, and 9 of cryodestruction of the arrhythmogenic areas. In a female patient, resection of the terminal crest and sinoatrial node followed by implantation of a pacemaker was performed in the AAI mode. Closed operations involved both transvenous electrodestruction of the arrhythmogenic areas (5 patients) and destruction of the His bundle with the development of complete transverse block and implantation of the pacemaker in the VVI mode. The best results were attained in young persons with Type I idiopathic atrial flutter where areas of fragmented and low-amplitude activity could be accurately specified.