Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros











Base de dados
Intervalo de ano de publicação
1.
J Gastrointest Cancer ; 55(2): 829-837, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38315330

RESUMO

BACKGROUND: Gastric cancer is a global health concern with varying clinical outcomes. This study aims to investigate the influence of preoperative Body Mass Index (BMI) on survival in patients who underwent curative resection for gastric cancer in Eastern India. METHODS: Data from a prospectively maintained Surgical Oncology database were analysed for patients who underwent curative resection for primary gastric adenocarcinoma between May 2016 and March 2022. Patients with incomplete data were excluded. Preoperative BMI was categorised into three groups: Underweight (< 18.5 kg/m2), Normal (18.5-22.9 kg/m2), and Overweight/Obese (=23 kg/m2). Clinicopathological details, short-term outcomes, and long-term oncological outcomes were assessed. Statistical analysis included survival estimates, Cox proportional hazard models, and subgroup analysis. RESULT: Of 162 patients, 145 met the inclusion criteria. Patients were predominantly male (68%) with middle or lower socioeconomic status. No significant differences amongst BMI groups were observed in performance score, tumour grade, clinical stage, or short-term outcomes. Postoperative complications and 30-day mortality were similar. However, underweight patients had poorer 4-year disease-free survival (DFS) compared to overweight/obese patients (14.3% vs. 39.7%, p = 0.03). Overweight/obese patients showed significantly better 4-year overall survival (OS) than underweight patients (47.8% vs. 20.4%, p = 0.03). CONCLUSIONS: In Eastern Indian gastric cancer patients undergoing curative resection, preoperative higher BMI (overweight/obese) was associated with better long-term survival. Understanding these findings could guide tailored interventions to improve outcomes in this population.


Assuntos
Índice de Massa Corporal , Neoplasias Gástricas , Humanos , Neoplasias Gástricas/cirurgia , Neoplasias Gástricas/mortalidade , Neoplasias Gástricas/patologia , Masculino , Feminino , Pessoa de Meia-Idade , Índia/epidemiologia , Idoso , Gastrectomia/estatística & dados numéricos , Complicações Pós-Operatórias/epidemiologia , Obesidade/complicações , Adenocarcinoma/cirurgia , Adenocarcinoma/mortalidade , Adenocarcinoma/patologia , Taxa de Sobrevida , Adulto , Período Pré-Operatório , Magreza/complicações , Estudos de Coortes , Prognóstico
2.
J Cancer Res Ther ; 19(Suppl 2): S991-S993, 2023 Jan 01.
Artigo em Inglês | MEDLINE | ID: mdl-38384099

RESUMO

ABSTRACT: Solitary fibrous tumor (SFT) is a fibroblastic mesenchymal neoplasm that rarely metastasizes. SFTs was first described in relation to pleura. However, occurrence of this tumor type has been reported in other sites like peritoneum, liver, adrenal gland, meninges and oral cavity. In head and neck region, oral cavity is the most common site of involvement. Most of the solitary fibrous tumors are benign and present as an asymptomatic slow growing mass. Surgery remains the mainstay of treatment. Hereby, we describe a case of 71-year-old male with malignant solitary fibrous tumor arising from right maxilla invading the right orbit presenting as proptosis.


Assuntos
Exoftalmia , Fibrossarcoma , Hemangiopericitoma , Tumores Fibrosos Solitários , Masculino , Humanos , Idoso , Maxila/diagnóstico por imagem , Maxila/cirurgia , Maxila/patologia , Tumores Fibrosos Solitários/diagnóstico , Tumores Fibrosos Solitários/cirurgia , Tumores Fibrosos Solitários/patologia , Boca/patologia , Exoftalmia/diagnóstico , Exoftalmia/etiologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA