The effect of acute and repeated ischemic preconditioning on recovery following exercise-induced muscle damage.

OBJECTIVES: The aim of this investigation was to determine if acute or repeated applications of ischemic preconditioning (IPC) could enhance the recovery process, following exercise induced muscle damage (EIMD). DESIGN: Randomized control trial. METHODS: Twenty-three healthy males were familiarised with the muscle damaging protocol (five sets of 20 drop jumps from a 0.6 m box) and randomly allocated to one of three groups: SHAM (3 × 5 min at 20 mmHg), Acute IPC (3 × 5 min at 220 mmHg) and Repeated IPC (3 days x 3 × 5 min at 220 mmHg). The indices of muscle damage measured included creatine kinase concentration ([CK]), thigh swelling, delayed onset muscle soreness, counter movement jumps (CMJ) and maximal voluntary isometric contraction (MVIC). RESULTS: Both acute and repeated IPC improved recovery in MVIC versus SHAM. Repeated IPC led to a faster MVIC recovery at 48 h (101.5%) relative to acute IPC (92.6%) and SHAM (84.4%) (P <  0.05). Less swelling was found for both acute and repeated IPC vs. SHAM (P <  0.05) but no group effects were found for CMJ, soreness or [CK] responses (P >  0.05). CONCLUSION: Taken together, repeated IPC can enhance recovery time of MVIC more than an acute application, and both reduce swelling following EIMD, relative to a SHAM condition.

The effect of intermittent lower limb occlusion on recovery following exercise-induced muscle damage: A randomized controlled trial.

OBJECTIVES: The purpose of this investigation was to examine the effectiveness of intermittent lower limb occlusion in augmenting recovery from exercise induced muscle damage (EIMD) in physically active males. DESIGN: Randomized controlled trial, double blind. METHODS: Sixteen healthy recreationally active male participants were randomly assigned to an intermittent occlusion (OCC; n=8) or control (SHAM; n=8) group. The EIMD protocol comprised of 100 drop-jumps, from a 0.6m box. Indices of muscle damage were creatine kinase (CK), thigh-circumference (TC), muscle soreness (DOMS), counter-movement jump (CMJ) and maximal isometric voluntary contraction (MIVC). Measurements were assessed pre, 24h, 48h and 72h following exercise. RESULTS: There was a significant time effect for all indices of muscle damage suggesting EIMD was present following the exercise protocol. The decrease in MIVC was significantly attenuated in the OCC group compared to the SHAM group at 24 (90.4±10.7 vs. 81.5±6.7%), 48 (96.2±6.1 vs. 84.5±7.1%) and 72h (101.1±4.2 vs. 89.7±7.5%). The CK response was reduced in the OCC group at 24 (335±87 vs. 636±300 IU) and 48h (244±70 vs. 393±248 IU), compared to the SHAM group. DOMS was significantly lower in the OCC compared to the SHAM group at 24, 48 and 72h post EIMD. There was no effect of OCC on CMJ or TC. CONCLUSIONS: This investigation shows that intermittent lower limb occlusion administered after a damaging bout of exercise reduces indices of muscle damage and accelerates the recovery in physically active males.