Parental Preconception Adversity and Offspring Mental Health in African Americans and Native Americans in the United States: A Systematic Review.

This systematic review examines the impact of parental preconception adversity on offspring mental health among African Americans (AAs) and Native Americans (NAs), two populations that have experienced historical trauma and currently experience ethnic/racial mental health disparities in the United States. PsycINFO, PubMed, CINAHL, Scopus, and Web of Science were searched for studies that included at least two generations of AAs or NAs from the same family, measured parental preconception adversity and their offspring's mental health, and examined the association between these variables. Over 3,200 articles were screened, and 18 articles representing 13 unique studies were included in this review. Among the studies with samples that included AAs (n = 12, 92%), 10 (83%) reported a significant association between parental preconception adversity and adverse offspring mental health. The only study with a sample of NAs (n = 1, 8%) also reported a significant association between these variables. Although the literature suggests that parental preconception adversity is associated with offspring mental health among AAs and NAs, it must be interpreted in the context of the small number of studies on this topic and the less-than-ideal samples utilized-just one study included a sample of NAs and several studies (n = 6, 46%) used multi-ethnic/racial samples without testing for ethnic/racial disparities in their results. A more rigorous body of literature on this topic is needed as it may help explain an important factor underlying ethnic/racial mental health disparities, with important implications for interventions and policy.

Parental Preconception Adversity and Offspring Health in African Americans: A Systematic Review of Intergenerational Studies.

Background: This systematic review explores the empirical literature addressing the association between parental preconception adversity and offspring physical health in African-American families. Method: We conducted a literature search in PubMed, Web of Science, PsycINFO, CINAHL, and Scopus through June 2021. Articles were included if they: reported data about at least two generations of African-American participants from the same family; measured parental preconception adversity at the individual level; measured at least one offspring physical health outcome; and examined associations between parental adversity and child health. Results: We identified 701 unique articles; thirty-eight articles representing 30 independent studies met inclusion criteria. Twenty-five studies (83%) reported that parental preconception adversity was associated with child health; six studies (20%) reported that parental preconception adversity was not associated with at least one offspring outcome; several studies reported both. Only six studies (20%) reported an association specific to African Americans. Conclusion: Empirical evidence linking parental preconception adversity with offspring physical health in African Americans is limited and mixed. In the current literature, very few studies report evidence addressing intergenerational associations between parental preconception adversity and offspring physical health in the African-American population, specifically, and even fewer investigate forms of parental preconception adversity that have been shown to disproportionately affect African Americans (e.g., racism). To better understand root causes of racial health disparities, more rigorous systematic research is needed to address how intergenerational transmission of historical and ongoing race-based trauma may impact offspring health among African Americans.

Associations between exposure to childhood bullying and abuse and adulthood outcomes in a representative national U.S. sample.

BACKGROUND: Negative childhood experiences are associated with poor health and psychosocial outcomes throughout one's lifespan. OBJECTIVE: We examined associations between childhood bullying and maltreatment and several adulthood outcomes: psychological distress, functional impairment, generalized fear, and physician-diagnosed mental and physical health ailments. The potential mediating role of recent negative life events was also explored. PARTICIPANTS AND SETTING: Data were collected through web-based surveys of a U.S. representative national sample of adults. METHODS: At Wave 1 (N = 3,598), participants reported exposure to negative childhood experiences; at Wave 2 (N = 3,497), physician-diagnosed mental and physical health ailments were provided; at Wave 3 (N = 2,906), participants reported exposure to recent negative life events and psychosocial outcomes. RESULTS: Of the sample, 26.29% (weighted n = 946) reported childhood bullying, 15.02% (weighted n = 540) reported physical abuse, 15.56% (weighted n = 560) reported witnessing parental violence, 11.42% (weighted n = 411) reported sexual abuse, and 8.64% (weighted n = 311) reported parental neglect. Respondents who reported bullying, physical abuse, or sexual abuse during childhood reported greater distress, functional impairment, and fear of the future in adulthood, as mediated through recent negative life events, compared to those who did not (ßs: 0.04-.06). Those reporting bullying, neglect, physical abuse, or sexual abuse in childhood reported more mental health ailments in adulthood (IRRs: 1.44-1.66) compared to those who did not. Those reporting bullying or sexual abuse in childhood reported more physical health ailments (IRRs: 1.25-1.39). CONCLUSIONS: Specific negative childhood experiences have unique links with poor outcomes in adulthood. Recent negative life events partially mediate these associations.

Neuropeptide Y impairs the acquisition of conditioned defeat in Syrian hamsters.

Recent evidence indicates that Neuropeptide Y (NPY) may function as a potent anxiolytic as well as a resilience factor that can insulate the brain from the effects of stress. However, most of these studies have utilized physical stressors such as shock or restraint. In the present study, we use an ethologically-based model in Syrian hamsters (Mesocricetus auratus) called Conditioned Defeat (CD) to investigate whether NPY can ameliorate the effect of social defeat stress. In the CD model, a male Syrian hamster is socially defeated by a larger, more aggressive conspecific. Subsequently, when paired with a smaller, non-aggressive intruder (NAI) in its own home cage, changes in its behavioral repertoire occur, including a reduction in aggression and chemosensory (social) investigation, and a concomitant increase in submissive behaviors. In Experiment 1, hamsters were infused intracerebroventricularly (icv) with NPY prior to social defeat, and 24-hours later, hamsters were exposed to a NAI. Results indicate that NPY significantly reduced submissive/defensive behaviors in socially defeated hamsters compared to control animals. In Experiment 2, we examined whether this effect was mediated by the NPY Y1 receptor. Subjects were first pre-treated with the Y1 receptor antagonist BIBP 3226 or vehicle, followed by NPY and then socially defeated. Upon testing with a NAI 24-hours later, pretreatment with BIBP 3226 failed to block the NPY effect compared to controls. These results demonstrate that NPY may function as an important resilience factor in socially defeated hamsters, but that these effects are not mediated by the Y1 receptor.

Tweeting negative emotion: An investigation of Twitter data in the aftermath of violence on college campuses.

Studying communities impacted by traumatic events is often costly, requires swift action to enter the field when disaster strikes, and may be invasive for some traumatized respondents. Typically, individuals are studied after the traumatic event with no baseline data against which to compare their postdisaster responses. Given these challenges, we used longitudinal Twitter data across 3 case studies to examine the impact of violence near or on college campuses in the communities of Isla Vista, CA, Flagstaff, AZ, and Roseburg, OR, compared with control communities, between 2014 and 2015. To identify users likely to live in each community, we sought Twitter accounts local to those communities and downloaded tweets of their respective followers. Tweets were then coded for the presence of event-related negative emotion words using a computerized text analysis method (Linguistic Inquiry and Word Count, LIWC). In Case Study 1, we observed an increase in postevent negative emotion expression among sampled followers after mass violence, and show how patterns of response appear differently based on the timeframe under scrutiny. In Case Study 2, we replicate the pattern of results among users in the control group from Case Study 1 after a campus shooting in that community killed 1 student. In Case Study 3, we replicate this pattern in another group of Twitter users likely to live in a community affected by a mass shooting. We discuss conducting trauma-related research using Twitter data and provide guidance to researchers interested in using Twitter to answer their own research questions in this domain. (PsycINFO Database Record