Evaluation of optical transmission across the ITER hard x-ray monitor system designed for the first plasma scenarios.

Hard x-ray (HXR) spectroscopy is applied for diagnostics of runaway electrons in nuclear fusion reactors. The scintillation counter is one of the most commonly used types of detectors for HXR spectroscopy. It consists of a detector that emits light when excited by HXR radiation (scintillator) directly coupled to a PMT (Photomultiplier Tube) that converts light pulses into an electrical signal. This type of detector is commonly used in existing tokamaks, such as Joint European Torus (JET), Experimental Advanced Superconducting Tokamak (EAST), Compact Assembly (COMPASS), and Axially Symmetric Divertor Experiment (ASDEX-U). In all these cases, the scintillator is directly coupled to the PMT to provide the best possible light transmission efficiency. The Hard X-ray Monitor (HXRM) is one among the first plasma diagnostic systems at ITER that provides information about the energy distribution of runaway electrons inside a tokamak by HXR spectroscopy. This system also uses a scintillator and a PMT as a detector. Due to the heavy shielding of the blanket modules, vacuum vessel, and port-plugs, it is not possible to assemble the scintillator outside the tokamak vacuum vessel. The PMT detector cannot be installed in the close vicinity of the tokamak due to either the significant magnetic field or temperature. A possible solution is to decouple the scintillator from the PMT and place the PMT inside the port-cell. Light pulses will be transmitted to the PMT via a 12 m long optical fiber bundle. Evaluation of the optical transmission was carried out to assess the performance of the HXR monitor and verify possible problems related to the PMT pulse discrimination under low light conditions.

Fast determination of indoor radon (222Rn) concentration using liquid scintillation counting.

The indoor 222Rn radionuclide was directly absorbed in typical 20 ml glass scintillation vials by passing -3 dm3 of ambient air through 16 ml of water-immiscible non-volataile scintillation cocktail Ultima-Gold F for 10 min. The activity of radon and its two α-emitting daughters: 218Po and 214Po, was determined with the BetaScout low-background liquid scintillation counter. The limit of 222Rn detection is 9 Bq/m3, and the quantification limit with 20% relative accuracy is 28 Bq/m3. The results of the indoor Rn measurement in different houses showed good consistency with results obtained from a Sarad EQF 3220 device.

Generation of the additional fluorescence radiation in the elastomeric shields used in computer tomography (CT).

Two commercially available (EP, Z) and eight new elastomeric composites (M1-M4, G1-G4, of thickness ≈1 mm) containing mixtures of differing proportions of heavy metal additives (Bi, W, Gd and Sb) have been synthesised and examined as protective shields. The intensity of the X-ray fluorescence radiation generated in the typical elastomeric shields for CT, containing Bi and other heavy metal additives influence on the practical shielding properties. A method for assessing the radiation shielding properties of elastomeric composites used in CT examination procedures via X-ray spectrometry has been proposed. To measure the radiation reduction ability of the protective shields, the dose reduction factor (DRF) has been determined. The lead equivalents for the examined composites were within the ranges of 0.046-0.128 and 0.048-0.130 mm for 122.1 and 136.5 keV photons, respectively. The proposed method, unlike to the common approach, includes a dose contribution from the induced X-ray fluorescence radiation of the heavy metal elements in the protective shields. The results clearly indicate that among the examined compositions, the highest values DRF have been achieved with preparations containing Bi+W, Bi+W+Gd and Bi+W+Sb mixtures with gradually decreasing content of heavy metal additives in the following order: Bi, W, Gd and Sb. The respective values of DRF obtained for the investigated composites were 21, 28 and 27 % dose reduction for a 1 mm thick shield and 39 and ~50 % for a 2 mm thick layer (M1-M4).

In search for new antipsoriatic agents: NAD topical composition.

The aim of the study was to examine the effectiveness of the oxidized form of nicotinamide adenine dinucleotide (NAD(+)), adenosine precursor, in 37 patients suffering from psoriasis. As NAD(+) is known to be relatively unstable, the second goal was to establish the proper conditions for the satisfactory stability of topical NAD(+) composition. In each patient, two matching plaques were selected for the study. Topical treatment with 1 or 0.3% NAD(+) in Vaseline ointment administered twice daily was compared with overnight therapy with 0.1% anthralin applied for 12 h and placebo. The enzymatic method was applied to determine the stability of NAD(+) in Vaseline ointment. After a 4-week application, the reduction in erythema, infiltration and desquamation caused by 1 or 0.3% topical NAD(+) composition was similar to the reduction caused by 0.1% anthralin. It was demonstrated that NAD(+) underwent a considerable decomposition at room temperature, while it was sufficiently stable at 5 degrees C; thus, for a longer use the agent should be stored at fridge temperature. NAD(+) therapy combines good efficacy, cosmetic acceptability and convenient twice-daily application.