1.
Br J Dermatol
; 157(6): 1291-3, 2007 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17927791
2.
Immunol Lett
; 64(1): 1-4, 1998 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9865594
RESUMO
Imuthiol (sodium-diethyl-dithiocarbamate, DTC) has been proven to possess immunomodulatory properties, this effect, however, varies in different model systems. This study was performed to assess the possible effect of imuthiol on etoposide-induced apoptosis in the human promyelocytic leukemia cell line, HL-60. In vitro pre-treatment with imuthiol at concentrations between 50 and 100 microM significantly inhibited etoposide-induced apoptosis of HL-60 cells, the inhibition appeared to be dose dependent. This effect may be associated with the immunomodulatory activity of imuthiol.
Assuntos
Apoptose/efeitos dos fármacos , Ditiocarb/farmacologia , Etoposídeo/antagonistas & inibidores , Tamanho Celular/efeitos dos fármacos , DNA/metabolismo , Fragmentação do DNA/efeitos dos fármacos , Relação Dose-Resposta a Droga , Etoposídeo/farmacologia , Citometria de Fluxo , Células HL-60 , Humanos , Fatores de Tempo , Células U937
3.
Magy Traumatol Orthop Helyreallito Seb
; 22(1): 53-60, 1979.
Artigo
em Húngaro
| MEDLINE
| ID: mdl-35712