Neurogenic Bladder and Acute Kidney Injury in Leukodystrophy.

Leukodystrophies are genetic white matter disorders. In the young, they represent an important cause of progressive neurological disability. Impairment of the bladder function may be part of the clinical picture of leukodystrophies. A neurogenic bladder is a dysfunctional urinary bladder caused by a disease of the central or peripheral nervous system involved in the control of micturition. In our patient, leukodystrophy-induced neurogenic bladder and acute kidney injury were revealed. If untreated, a neurogenic bladder can cause renal failure and urinary incontinence. Patients with a neurogenic bladder should be monitored, and management should aim to preserve renal function and achieve social continence.

Neurobrucellosis Presented by Cerebral Salt Wasting.

This case reported here was a 27-year-old female patient, and she had no chronic disease other than hypothyroidism. She was brought to the ER with complaints of fever, chills, weakness, and hyponatremia. She has been diagnosed with brucellosis using a serum tube agglutination test (STAT). Cerebrospinal fluid (CSF) analysis and brain MRI findings supported the central nervous system (CNS) involvement of the brucella. Despite intense 3% NaCl hydration, her hyponatremia was persisting. Sodium stabilized on the 14th day when the antibrucellosis treatment effect was settled. Hyponatremia was attributed to cerebral salt wasting (CSW) due to neurobrucellosis.