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1.
Phys Rev Lett ; 128(17): 174802, 2022 Apr 29.
Artigo em Inglês | MEDLINE | ID: mdl-35570451

RESUMO

Relativistic interactions between ultraintense (>10^{18} W cm^{-2}) laser pulses and magnetized underdense plasmas are known to produce few-cycle Cerenkov wake radiation in the terahertz (THz) domain. Using multidimensional particle-in-cell simulations, we demonstrate the possibility of generating high-field (>100 GV m^{-1}) THz bursts from helium gas plasmas embedded in strong (>100 T) magnetic fields perpendicular to the laser path. We show that two criteria must be satisfied for efficient THz generation. First, the plasma density should be adjusted to the laser pulse duration for a strong resonant excitation of the electromagnetic plasma wake. Second, in order to mitigate the damping of the transverse wake component across the density gradients at the plasma exit, the ratio of the relativistic electron cyclotron and plasma frequencies must be chosen slightly above unity, but not too large, lest the wake be degraded. Such conditions lead the outgoing THz wave to surpass in amplitude the electrostatic wakefield induced in a similar, yet unmagnetized plasma.

2.
Mol Biol Evol ; 12(6): 1074-84, 1995 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-8524041

RESUMO

Similar microsatellite electromorphs (PCR products of the same size) can arise from independent mutational events. Such alleles are not identical by descent. This phenomenon, termed size homoplasy, was studied by sequencing electromorphs of two microsatellite loci in which the stretch of basic repeats is interrupted by different short (1-2 bp) DNA motifs. The number and position of these interruptions were established for electromorphs from closely and distantly related populations of honeybees and bumblebees. No sequence difference was found when electromorphs came from the same subspecies or from closely related subspecies, suggesting that they were probably identical by descent. In contrast, sequence differences were often detected in distantly related subspecies, showing that size homoplasy frequently occurs at this level of population differentiation. Size homoplasy is increased by limits to free length variation of alleles, a phenomenon that seems to act on interrupted microsatellites when comparing distantly related taxa, that is, honeybee subspecies from different evolutionary lineages. Electromorph sequences suggest that, within the scope of these limits, large mutation events have occurred frequently at both interrupted loci studied. In good agreement with the molecular data, computations based on the observed heterozygosity and number of electromorphs and simulation studies showed that neither locus fits the one-step stepwise mutant model (SMM). We speculate that interrupted microsatellites in general could be characterized by a higher variance in repeat number and consequently a lower homoplasy rate than pure ones. Hence, interrupted microsatellites should be most appropriate for investigating population differentiation and evolutionary relationship between relatively distant populations.


Assuntos
Abelhas/genética , Repetições de Microssatélites , Mutação , Reação em Cadeia da Polimerase , Alelos , Animais , Sequência de Bases , Simulação por Computador , DNA/química , DNA/genética , Eletroforese , Evolução Molecular , Feminino , Masculino , Modelos Genéticos , Dados de Sequência Molecular , Especificidade da Espécie
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