1.
Org Lett
; 11(11): 2233-6, 2009 Jun 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19473042
RESUMO
The regioselective synthesis of chafurosides A (1) and B (2) from the same methyl ketone 5 was accomplished using a novel protecting group strategy. Both flavone rings were constructed from beta-diketone intermediate 4, which was readily obtained by condensation of an acyl donor and ketone 5. Construction of the dihydrofuran ring was achieved via an intramolecular Mitsunobu reaction.