1.
J Org Chem
; 87(12): 8118-8125, 2022 Jun 17.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35657258
RESUMO
N-Methyl-2-methoxymethylanilines 1 bearing various 5-substituted-pyrimidin-2-yl groups were prepared, and their rotational behaviors were explored in detail. It was revealed that the rotational barriers around two N-Ar bonds increase in proportion to the electron-withdrawing ability of substituents X at the 5-position.