RESUMO
Root growth promoters, 4-hydroxykigelin (1) and 6-demethylkigelin (2), together with 6-hydroxymellein (3) were isolated from cultures of the fungus Aspergillus terreus and their structures were identified by spectroscopic analysis. The biological activities of the three dihydroisocoumarins, 1, 2, and 3, have been examined using a bioassay method with lettuce seedlings. Furthermore, interactions between the dihydroisocoumarins and indole-3-acetic acid against the root growth have been examined.
Assuntos
Aspergillus/química , Aspergillus/isolamento & purificação , Cumarínicos/isolamento & purificação , Cumarínicos/farmacologia , Substâncias de Crescimento/isolamento & purificação , Raízes de Plantas/química , Raízes de Plantas/crescimento & desenvolvimento , Substâncias de Crescimento/farmacologia , Lactuca/efeitos dos fármacos , Lactuca/crescimento & desenvolvimento , Modelos Moleculares , Estrutura Molecular , Raízes de Plantas/efeitos dos fármacos , Microbiologia do SoloRESUMO
Aspterric Acid, 6-Hydroxymellein, Arabidopsis thaliana, Aspergillus terreus Aspterric acid (1) and 6-hydroxymellein (2), inhibitors of pollen development in Arabidopsis thaliana, have been isolated from the fungus Aspergillus terreus. 1 and 2 inhibited the pollen development at concentrations of 38 and 52 microM, respectively. The microscopic examination of pollen development suggested that the inhibition by the treatment with 1 caused at meiosis and the inhibition by the treatment with 2 caused at microspore stage. 1 and 2 could be useful agents for the molecular investigation of anther and pollen development in higher plants.
