Assuntos
Humanos , Feminino , Adulto , Neoplasias do Colo do Útero/complicações , Neoplasias do Colo do Útero , Colo do Útero/patologia , Colo do Útero , Fluordesoxiglucose F18 , Metástase Neoplásica/patologia , Metástase Neoplásica , Neoplasias do Colo do Útero/tratamento farmacológico , Neoplasias do Colo do Útero/radioterapia , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada/métodos , Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada/tendências , Tomografia por Emissão de Pósitrons combinada à Tomografia ComputadorizadaAssuntos
Carcinoma/diagnóstico , Carcinoma/secundário , Fluordesoxiglucose F18 , Imagem Multimodal , Neoplasias Musculares/diagnóstico , Neoplasias Musculares/secundário , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos , Neoplasias de Tecidos Moles/diagnóstico , Neoplasias de Tecidos Moles/secundário , Tela Subcutânea , Tomografia Computadorizada por Raios X , Neoplasias do Colo do Útero/patologia , Quimiorradioterapia , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasias do Colo do Útero/terapiaAssuntos
Neoplasias das Glândulas Suprarrenais/secundário , Carcinoma Neuroendócrino/secundário , Fluordesoxiglucose F18 , Imagem Multimodal , Neoplasias Ovarianas/patologia , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos , Tomografia Computadorizada por Raios X , Neoplasias das Glândulas Suprarrenais/diagnóstico por imagem , Idoso , Carcinoma Neuroendócrino/diagnóstico por imagem , Carcinoma Neuroendócrino/tratamento farmacológico , Carcinoma Neuroendócrino/cirurgia , Terapia Combinada , Feminino , Humanos , Histerectomia , Neoplasias Ovarianas/diagnóstico por imagem , Neoplasias Ovarianas/tratamento farmacológico , Neoplasias Ovarianas/cirurgia , Ovariectomia , SalpingectomiaRESUMO
BACKGROUND: Krukenberg tumor is a metastatic ovarian tumor with primary focus usually seen in the gastrointestinal tract. Metastatic involvement of the ovary is an uncommon manifestation of malignancy. We report a [18F]-fluoro-2-deoxy-D-glucose positron-emission tomography/computed tomography (FDG PET/CT) appearance of solitary unilateral ovarian metastasis in a 44-year-old woman with a history of mucinous adenocarcinoma type of gastric carcinoma. Total hysterectomy with bilateral salpingo-oophorectomy was performed. Histopathological verification determined metastasis of mucinous adenocarcinoma with components of signet-ring cell carcinoma in the right ovary.
Assuntos
Adenocarcinoma Mucinoso/secundário , Fluordesoxiglucose F18 , Imagem Multimodal/métodos , Neoplasias Ovarianas/secundário , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos , Neoplasias Gástricas/patologia , Tomografia Computadorizada por Raios X , Adenocarcinoma Mucinoso/diagnóstico por imagem , Adulto , Feminino , Humanos , Neoplasias Ovarianas/diagnóstico por imagemRESUMO
PURPOSE: The aim of the current study was to determine the diagnostic accuracy of whole-body 18F-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in detecting carcinoma of unknown primary (CUP). MATERIALS AND METHODS: A total of 7,636 patients were investigated by FDG-PET/CT examinations at our Institution. We retrospectively evaluated the file records of 432 patients who were referred to FDG PET/CT imaging with a diagnosis of cancer of unknown primary, and included 316 of the patients with histopathologic verification at the final diagnosis. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy were calculated. The Kaplan-Meier test was used for survival analysis. Median survival rate was calculated to evaluate the prognostic value of the FDG-PET/ CT findings. RESULTS: In the search for a primary, FDG-PET/CT findings correctly diagnosed lesions as the site of the primary true positive in 238 cases, 10 findings diagnosed no site of a primary and none was subsequently proven true negative, 12 diagnoses were false positive and 56 were false negative. The sensitivity of FDG-PET/CT is 81% and the specificity 45%. Positive predictive value, negative predictive value and diagnostic accuracy were 95%, 15% and 78%, respectively. CONCLUSIONS: Whole-body FDG-PET/CT imaging is proven to be useful method in the search for the primary focus and metastases in patients with cancer of unknown primary.