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1.
Intern Med ; 63(3): 407-411, 2024 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-37316270

RESUMO

A 74-year-old woman with an implanted physiological DDD pacemaker visited our department complaining of palpitations due to atrial fibrillation (AF). Catheter ablation therapy for AF was scheduled. Preoperative multidetector computed tomography showed that the inferior pulmonary vein (PV) was a common trunk, and the left and right superior PVs branched from the center of the left atrial roof. In addition, mapping of the left atrium before AF ablation revealed no potential in either the inferior PV or common trunk. We performed left and right superior PV and posterior wall isolation. After ablation, AF was not observed on pacemaker recordings.


Assuntos
Fibrilação Atrial , Ablação por Cateter , Veias Pulmonares , Feminino , Humanos , Idoso , Veias Pulmonares/diagnóstico por imagem , Veias Pulmonares/cirurgia , Fibrilação Atrial/cirurgia , Átrios do Coração/cirurgia , Tomografia Computadorizada Multidetectores , Ablação por Cateter/métodos , Resultado do Tratamento
2.
J Cardiol ; 83(4): 243-249, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37684004

RESUMO

BACKGROUND: Although mild cognitive impairment (MCI) has received much attention as a precursor of dementia, its prognostic role has not been fully clarified in patients with heart failure (HF). METHODS AND RESULTS: We studied 274 patients admitted for acute decompensated HF. Cognitive function was evaluated using Mini Mental State Examination (MMSE). According to the previous definition, MMSE of 0-23, 24-27, and 28-30 were classified as CI (n = 132), MCI (n = 81), and normal cognitive function (n = 61). The primary endpoint was cardiac events, defined as the composite of unplanned HF hospitalization and cardiovascular mortality. During a mean follow-up period of 4.9 ±â€¯3.1 years, 145 patients experienced cardiac events. Multivariable logistic regression analysis showed that hypertension (p = 0.043), low cardiac index (p = 0.022), and low serum albumin level (p = 0.041) had a significant association with cognitive abnormalities. Both CI and MCI were significantly associated with cardiac events after Cox multivariable adjustment [CI: p = 0.001, adjusted HR 2.66 (1.48-4.77); MCI: p = 0.025, adjusted HR 1.90 (1.09-3.31), normal cognitive function group: reference]. Patients with MCI had a significantly higher risk of unplanned HF hospitalization [p = 0.033, adjusted HR 1.91 (1.05-3.47)], but not all-cause mortality (p = 0.533) or cardiovascular mortality (p = 0.920), while CI was significantly associated with all-cause mortality (p = 0.025) and cardiovascular mortality (p = 0.036). CONCLUSION: Even MCI had a significant risk of cardiac events in patients with acute decompensated HF. This risk was mainly derived from unplanned HF hospitalization.


Assuntos
Disfunção Cognitiva , Insuficiência Cardíaca , Humanos , Relevância Clínica , Disfunção Cognitiva/etiologia , Disfunção Cognitiva/diagnóstico , Insuficiência Cardíaca/complicações , Cognição , Testes de Estado Mental e Demência
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