[Specifics of surgical approach in purulent cholangitis]. / Osobennosti khirurgicheskoi taktiki pri gnoinom kholangite.

When analysing the results of examination of 773 patients with obstructive jaundice (OJ) of benign genesis, purulent cholangitis (PC) was revealed in 323. In PC diagnosis, the ultrasound study is a valuable adjunctive method. In presence of the clinical signs of PC in patients and absence of the effect from conservative therapy, and as well in preservation of the high indices of bilirubinemia, the early operative treatment performed, as a rule, no later than 48 h after hospitalization is indicated. PC in patients with OJ is most frequently caused by choledocholithiasis. The causative agents of PC are represented by aerobic and anaerobic microorganisms, requiring the use of broad spectrum antibiotics before the operation and 6-12 h after it. Adequate restoration of bile passage and pathogenetically substantiated local influencing upon the inflammatory process in the bile ducts are tasks of operative intervention. Direct administration into the bile ducts of antibiotics and antiinflammatory preparations, in particular of quercitrol, via the external drain of the common bile duct is expedient.

[Use of stachyrene in combined treatment of patients with obstructive jaundice]. / Primenenie stakhirena v kompleksnom lechenii bol'nykh s obturatsionnoi zheltukhoi.

In 49 patients with obstructive jaundice of various genesis progressive cholemic intoxication in absence of the effect from conventional detoxication therapy, the Stachyrene preparation, which contains as an effective agent the polyphenol compounds of Stachys recta L., was used. Stachyrene was administered before and after the operation. Under the influence of the preparation in the majority of patients, the more rapid normalization of the indices of homeostasis occurred. The most pronounced effect was noted in patients with obstructive jaundice of benign genesis.