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1.
Science ; 192(4238): 471-3, 1976 Apr 30.
Artigo em Inglês | MEDLINE | ID: mdl-176728

RESUMO

Norepinephrine increases the intracellular level of adenosine 3',5'-monophosphate (cyclic AMP) in clonal cell lines of nerve, glia, smooth muscel, and skeletal muscle. The largest response is in skeletal muscle, where the cyclic nucleotide concentration is elevated more than 500-fold. Glia and muscle cells, but not nerve cells, respond to dopamine with increased cyclic AMP accumulation. This response appears to be mediated through a beta-adrenoreceptor.


Assuntos
AMP Cíclico/metabolismo , Músculos/metabolismo , Neuroglia/metabolismo , Neurônios/metabolismo , Linhagem Celular , Receptores Adrenérgicos
3.
Proc Natl Acad Sci U S A ; 71(6): 2377-81, 1974 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-4366764

RESUMO

The regulation of the specific activities of adenylate kinase (EC 2.7.4.3) and creatine kinase (EC 2.7.3.2) in myogenic cell lines is independent of cell fusion. The observed increases in enzyme specific activities are cell density dependent, and may be further broken down into contributions from an increase in enzyme activity per cell and a decrease in protein per cell. Only the former appears to be affected by medium conditioning.


Assuntos
Creatina Quinase/metabolismo , Músculos/embriologia , Fosfotransferases/metabolismo , Animais , Contagem de Células , Diferenciação Celular , Fusão Celular , Linhagem Celular , Músculos/enzimologia , Ratos
9.
J Virol ; 3(6): 623-6, 1969 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-4307906

RESUMO

Cytoplasmic particles which sedimented at 150S were the smallest structures containing detectable viral ribonucleic acid polymerase in mouse cells infected with encephalomyocarditis virus.


Assuntos
Vírus da Encefalomiocardite/enzimologia , RNA Nucleotidiltransferases , RNA Viral/biossíntese , Isótopos de Carbono , Técnicas de Cultura , Citoplasma , Nucleotídeos de Guanina/metabolismo , Membranas , Microscopia Eletrônica , Neoplasias Experimentais , Isótopos de Fósforo , RNA Nucleotidiltransferases/isolamento & purificação
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