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1.
Ann Cardiol Angeiol (Paris) ; 57(1): 58-61, 2008 Feb.
Artigo em Francês | MEDLINE | ID: mdl-17568556

RESUMO

In some countries, Hydatidosis is a common public health problem but cardiac hydatid cysts are rarely observed. The evaluations of operative results and follow up of cardiac hydatid cases. Twenty-five consecutive unselected patients suffering from cardiac hydatidosis and operated on between 1967 and 2006 in Siyami Ersek Cardiothoracic and Vascular Surgery Center were retrospectively analyzed. In 10 of these patients the hydatid cyst was intracardiac, while in 13 patients cysts were extracavitary but located into the pericardium. In 2 patients the hydatid cyst was both intra and extracavitary. Mean age of the patients was 31+/-9.2. The female/male ratio was 17/8. The 12 patients with intracavitary and 2 patients wit extracavitary hydatid cysts were operated on with the aid of extracorporeal circulation. One patient died postoperatively. In one patient recurrence of the hydatidosis was observed. The majority of cases in previous publications were located in the left side of the heart. In our series, most were located in the right heart. In such cases clamping the pulmonary artery is mandatory to prevent pulmonary migration. Careful resection is important for prevention of recurrence.


Assuntos
Equinococose/cirurgia , Cardiopatias/parasitologia , Cardiopatias/cirurgia , Adolescente , Adulto , Animais , Antinematódeos/uso terapêutico , Ecocardiografia , Circulação Extracorpórea , Feminino , Humanos , Masculino , Mebendazol/uso terapêutico , Pessoa de Meia-Idade , Estudos Retrospectivos
2.
J Int Med Res ; 33(4): 397-405, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16104443

RESUMO

Levosimendan is a calcium sensitizer that demonstrates enhanced myocardial contractility. There is little information concerning the effect of levosimendan on left ventricular tissue parameters and exercise capacity. We evaluated the effects of a 24-h course of levosimendan therapy on cardiac tissue parameters in 30 patients, aged 48 - 70 years, admitted to our hospital for the management of decompensated heart failure. All patients underwent echocardiographic examination using tissue Doppler imaging (TDI) and a 6-min walk test. Systolic myocardial velocity of the mitral annulus (Sm) was significantly increased in levosimendan-treated patients compared with placebo-treated patients. There was a positive correlation between Sm and exercise capacity. Levosimendan might be expected to increase cardiac contractile force, especially Sm velocity, in parallel with exercise tolerance. The study has also shown that the progress of ventricular function after levosimendan treatment in patients with exercise intolerance could be monitored effectively by Sm velocity measurements using TDI.


Assuntos
Cardiotônicos/farmacologia , Tolerância ao Exercício/efeitos dos fármacos , Exercício Físico , Hidrazonas/farmacologia , Piridazinas/farmacologia , Função Ventricular Esquerda/efeitos dos fármacos , Remodelação Ventricular/efeitos dos fármacos , Idoso , Cálcio/metabolismo , Técnicas de Diagnóstico Cardiovascular , Ecocardiografia , Ecocardiografia Doppler , Feminino , Insuficiência Cardíaca/terapia , Humanos , Masculino , Pessoa de Meia-Idade , Valva Mitral/patologia , Contração Miocárdica , Simendana , Fatores de Tempo , Disfunção Ventricular Esquerda/tratamento farmacológico , Caminhada
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