Fracture of the cobalt-chromium modular femoral neck component in total hip arthroplasty.

Total hip prostheses using cervico-metaphyseal modularity were designed to better replicate the geometry of the native extra-medullary femur. However, they are associated with numerous complications including corrosion, disassembly, pseudotumours and, most notably, fractures of the modular neck. All reported cases of modular neck fractures occurred with titanium components (Ti-6Al-4V). To prevent this weakness, manufacturers developed modular necks made of cobalt-chromium (Co-Cr). We report a fracture of a long, 8° varus, Co-Cr modular neck connected to a 36-mm short (-3.5mm) femoral head. The fracture occurred 22 months post-implantation in a woman who had a low level of physical activity and a body mass index of 28.7 kg/m(2). To our knowledge, this case is the first reported instance of Co-Cr modular neck fracture. It may challenge the wisdom of further developing this modularity design, as our patient had none of the known risk factors for modular neck fracture. In addition, cases of pseudotumour have been reported with Co-Cr modular necks subjected to fretting corrosion, which contributed to the fracture in our patient.

Mid-term outcomes after distally locked-to-standard primary stem exchange in 29 hip-prosthesis patients.

BACKGROUND: Cementless locked femoral stems are used for revision surgery in patients with bone loss to induce spontaneous bone reconstruction, allowing subsequent replacement by a standard primary stem. The small number of patients and short follow-ups available to date preclude a valid assessment of this strategy. HYPOTHESIS: After distally locked stem revision, replacement by a standard primary stem does not induce complications, and the quality of the bone reconstruction allows strong fixation of a regular primary stem. MATERIALS AND METHODS: We retrospectively evaluated 29 patients in whom a distally locked femoral stem was replaced by a standard primary stem between 1998 and 2010 (cemented in 27, cementless in 2 cases). The reason for the procedure was stem breakage, stem migration, or thigh pain. Mean patient age was 63 years (range, 39-78 years). Outcomes were evaluated based on the Postel-Merle d'Aubigné [PMA] score and Harris Hip Score [HHS]. In addition, radiographs were obtained to assess prosthesis fixation and the Hofmann cortical index measured the bone reconstruction. RESULTS: The distally locked stem was removed via a postero-lateral approach without femoral osteotomy in all the 29 cases. In one patient, an intra-operative fracture occurred during femoral preparation. Mean follow-up after the exchange procedure was 75 months (range, 3-188 months). Postoperative ccomplications occurred in 9 (32%) patients and consisted of chronic infection in 2 patients (after 3 and 76 months), post-traumatic peri-prosthetic fractures treated with internal fixation in 3 patients (after 100, 138, and 182 months), aseptic loosening in 3 patients (after 13, 39, and 122 months), and recurrent instability in one patient (after 63 months). All cause revision stem survival after 75 months was 72% (95% confidence interval, 47%-87%). In the 19 patients who still had their revision stem at last follow-up, the mean PMA score was 16.7 (range, 13-18) and the mean HHS was 88.2 (range, 59-99). The Hofmann index remained unchanged [36.5% (range, 28%-58%) before the exchange and 32.9% (range, 20%-57%) after the exchange; P=0.129]. DISCUSSION: This study confirms the feasibility of substituting a distally locked stem with a standard primary stem. No specific complications occurred and no technical difficulties arose when extracting the long stems. However, the 32% complication rate and, more specifically, the occurrence of loosening in 10% (3/29) of patients mandates caution in the use of this technique, which should not be proposed routinely, and suggests a need for considering cementless fixation of the standard primary stem. LEVEL OF EVIDENCE: Level IV, retrospective study.

One-year prospective comparative study of three large-diameter metal-on-metal total hip prostheses: serum metal ion levels and clinical outcomes.

INTRODUCTION: The good clinical outcomes and low wear obtained with 28-mm metal-on-metal implants for total hip replacement prompted the development of large-diameter heads that more closely replicated the normal hip anatomy, with the goal of improving prosthesis stability. However, the blood release of metal ions due to wear at the bearing surfaces and the high rate of groin pain seen with large-diameter implants are causing concern. To determine whether these events are related to the geometry and metal composition of the prosthesis components, we conducted a prospective study of clinical outcomes and serum chromium and cobalt levels 1 year after implantation of three different acetabular cups. HYPOTHESIS: Serum levels of metal ions are comparable with different types of large-diameter metal-on-metal total hip prostheses. PATIENTS AND METHODS: We compared 24 Durom™ cups (D), 23 M2a Magnum™ cups (M2a), and 20 Conserve Total™ (C) cups regarding serum chromium and cobalt levels, Postel-Merle d'Aubigné (PMA) scores and Oxford Hip Scores (OHS), as well as radiographic cup orientation and position at 1-year follow-up. Mean age was 66 years (45-85 years), mean body mass index was 28 Kg/m(2) (18-45), patients were almost equally divided between males and females, and the reason for hip replacement was primary hip osteoarthritis in 65 patients and avascular necrosis in two. Metal ions were assayed in serum from blood drawn through non-metallic catheters, using mass spectrometry. RESULTS: Dislocation occurred in two patients (one D and one M2a) and revision to change the bearing couple was required in two patients in the D group. Serum cobalt levels in the C group were significantly higher (P=0. 0003) than in the two other groups (7.5 µg/L versus 2. 7 µg/L with D and 2. 2 µg/L with M2a). Clinical outcomes were better in the M2a group (PMA, 17.7 [16-18]; and OHS, 15.2 [12-30]; P<0.05). The PMA score and OHS were 17.5 (16-18) and 18.2 (12-42), respectively, with D; and 16.75 (10-18) and 22. 2 (12-42), respectively, with C cups. When all three cup models were pooled, serum ion levels were higher in patients with pain than without pain (chromium, 7.1 µg/L versus 2.1 µg/L [P=0.002], and cobalt, 8 µg/L versus 2.6 µg/L [P=0.0004]). DISCUSSION: Serum chrome and cobalt levels increased after metal-on-metal total hip replacement, and the increase was greater with large-diameter implants than previously reported with 28-mm implants. Persistent pain was significantly associated with higher metal ion levels, with a probable cobalt cut-off of about 8 µg/L. Differences in modular head-neck concepts may explain the observed variations.