1.
Bioorg Med Chem Lett
; 19(19): 5569-72, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19726183
RESUMO
Solvent free multicomponent reaction of Baylis Hillman acetate, TMS azide and arylnitrile to produce 1,5-disubstituted tetrazole is described. Some of these tetrazoles are found to be potential TNF-alpha inhibitors.