Toxicological aspects of preclinical studies of hemosorbents.

The main tendencies in the development of methods for hemo- and lymphosorption are considered. Base toxicological requirements to sorbents have been formulated. Special attention is paid to possible tox effects of sorbents containing carcinogenic admixtures. The importance of choosing appropriate methods sorbents' sterilization or conservation has been emphasized. Results of studies of various sorbents a presented.

[The results of toxicological research on dental alloys containing Ni, Cr and Co using the implantation method]. / Rezul'taty toksikologicheskogo issledovaniia stomatologicheskikh splavov, soderzhashchikh Ni, Cr, Co, metodom implantatsii.

Biocompatibility of 7 dentistry alloys containing 5 do 70% of Ni but not containing Be was studied by implantation of these alloys into femoral muscles of 360 white rats. Tissue directly adjacent to alloy samples, regional lymph nodes, and viscera were under study. The detected changes were approximately similar in different animal groups and similar to the changes in the reference group, this permitting the authors to consider the suggested allows biologically indifferent.