RESUMO
This study examined cancer research stories on the BBC web archive (July 1998-June 2006). There were about 260 BBC stories per year, of which about 170 were classed as relevant to reports of cancer research. The stories focused heavily on breast cancer, and over one-third of them mentioned this (compared with a cancer disease burden of 13%); the next most covered sites were lung and prostate cancers, although the former was much less mentioned than its cancer disease burden of almost 20% would have suggested. The focus of the stories was often on new or improved drugs or vaccines (20% of stories), with lifestyle choices (12%), genetic developments (9%), and food and drink (8%) also featuring fairly prominently. The BBC stories cited about 1380 research papers that could be identified as journal articles. About three-quarters of the cited papers were in the field of cancer. The papers of these authors came from over 60 countries, and 40% were from the United Kingdom and 36% from the United States. UK cancer research was heavily overcited, by about 6:1, relative to its presence in world oncology research and US research was cited about in proportion. That of most other countries, especially Japan, Germany, and Austria, was relatively undercited. These cited papers also acknowledged more funding bodies. Most of the BBC stories were put in context by external commentators, of whom the large majority was from the UK's cancer research charities.
Assuntos
Pesquisa Biomédica/estatística & dados numéricos , Internet/estatística & dados numéricos , Meios de Comunicação de Massa/estatística & dados numéricos , Oncologia/estatística & dados numéricos , Humanos , Neoplasias/diagnóstico , Neoplasias/terapia , Editoração , Reino UnidoRESUMO
New Jersey Caucasian, African American, and Hispanic genotype and allele frequencies were determined for the six PCR-based loci, HLA-DQA1, LDLR, GYPA, HBGG, D7S8, and Gc. All but one locus (HLA-DQA1 for African Americans) meet Hardy-Weinberg expectations. However, observing one departure in 18 loci over the three New Jersey sample populations is not unexpected. There is little evidence for departures from independence between pairs of loci in the three populations studied. Thus, multiple locus profile frequencies can be determined using the product rule.
Assuntos
População Negra/genética , DNA/análise , Genética Populacional , Hispânico ou Latino/genética , População Branca/genética , Alelos , Impressões Digitais de DNA/métodos , Frequência do Gene , Marcadores Genéticos , Genótipo , Glucanos/genética , Glicoforinas/genética , Antígenos HLA-DQ/genética , Cadeias alfa de HLA-DQ , Humanos , New Jersey , Reação em Cadeia da Polimerase , Polimorfismo Genético/genética , Receptores de LDL/genética , Proteína de Ligação a Vitamina D/genéticaRESUMO
Allele frequencies for six PCR-based loci and three protein-based (i.e., enzyme systems) loci were determined in a Caucasian sample population from New Jersey. The loci are LDLR, GYPA, HBGG, D7S8, Gc, HLA-DQA1, PGM1, ESD, and EAP. All loci meet Hardy-Weinberg expectations. In addition, there is little evidence for association of alleles among the nine loci. The allelic frequency data generally are similar to another Caucasian population database.
