[L. E. Golubinin, the Professor of the Moscow University and His Role in History of National Clinic of Beginning of XX Century].

The article presents the scientific biography of L. E. Golubinin, the prominent therapist, prepared on the basis of publications' review and rich archive materials, including documents of the Central Historical Archive of Moscow (f.418) and personal archive of V. D. Shervinsky from the Department of History of Medicine of The Federal State Budget Scientific Institution "N. A. Semashko National Research Institute of Public Health". For the first time the role L. E. Golubinin played in organization of the scientific school of Shervinsky-Golubinin asd a largest therapeutic school in the Moscow University is revealed. Also a high moral level of the personality of L. E. Golubinin is presented.

[The therapeutic clinics of the Moscow University at the turn of XIX-XX centuries: the comparative characteristic of scientific schools of Zakhariin, Ostroumov and Shervinskii-Golubinin].

The materials are analyzed characterizing scientific therapeutic schools organized in the Moscow university at the turn of XIX-XX centuries by G.A. Zahar'in, A.A. Ostroumov and V.D. Shervinskii (collaboratively with L.E. Golubinin). It is demonstrated that in the 1890s the leadership passed from faculty therapy of Zahar'in to hospital therapy of Ostroumov. The school of Shervinskii-Golubinin played decisive role in further development of therapeutic clinic in Russia and after that in its restoration in the USSR. It is emphasized that the case in question is just scientific schools but not their founders - Zahar'in and Ostroumov. The both of them are justifiably referred to initiators of national clinic of intern diseases.

[The Moscow Stomatological Institute as a third Moscow medical institute].

The article presents a short history of three third medical institutes existed in Moscow in different time.

[Moscow therapeutic schools (from the 1920s to the 1940s)].

Six leading Moscow therapeutic schools in the 1920s to the 1940s are first identified and given in this paper; their personal composition, distinctive characteristics, and role in the history of Russian internal medicine are shown.

[Hypertensive crisis: pathogenesis, clinic, treatment].

Contemporary data on mechanisms of development, types, and clinical picture of hypertensive crisis (HC) are presented. Algorithms of rational therapy of uncomplicated and complicated HC are considered. Appropriateness of the use in HC of antihypertensive drugs with multifactorial action is stressed. These drugs include urapidil - an antihypertensive agent with complex mechanism of action. Blocking mainly the postsynaptic 1-adrenoreceptors urapidil attenuates vasoconstrictor effect of catecholamines and decreases total peripheral resistance. Stimulation of 5HT1-receptors of medullary vasculomotor center promotes lowering of elevated vascular tone and prevents development of reflex tachycardia.

[Ivan Alekseevich Chernogorov--the professor-cardiologist of the Moscow Stomatologic Institute].

The article presents the scientific biography of Ivan Alekseyevitch Tchernogorov, the prominent Moscow cardiologist, the disciple of D.D. Pletnyev and VF Zelenin.

[About the clinical school of D.D. Pletnev: Professor B.A. Egorov (1889-1963)].

The article considers the issues of clinical school created in the first half of XX century by D.D. Pletniyev, one of the founders of therapy in the USSR. The article for the first time presents the scientific biography and complicated course of life of B.A. Yegorov, one of the leading representatives of this school.

[To the centennial of the myocardial infarction. Priorities of domestic researchers in the study of the problem of modern cardiology].

There are domestic priorities in the 100-year history of myocardial infarction research a description of the disease clinical picture by V.P.Obrazcov and N.D.Strazhesko, development of mammary-coronary bypass by V.I.Kolesov, intracoronary thrombolysis by E.I.Chazov et al.

[The A.N. Kriukov scientific therapeutic school].

The article deals with the additions and specifications to the biography of A.N. Kryukov. For the first time, the general therapeutic scientific school created by him is analyzed. The formation within this school of the comprehensive clinical hematological school of Kryukov-Kassirsky which took a leadership in national hematology of XX century is considered.

[Clinical effectiveness of beta-adrenoblockers and their effects on copulative function in patients with hypertension]. / Klinicheskaia éffektivnost' i vliianie beta-adrenoblokatorov na kopuliativnuiu funktsiiu u bol'nykh s arterial'noi gipertenziei.

Twenty four hour blood pressure and ECG monitoring, assessment of sexual function (questionnaires, penile artery Doppler flowmetry) were carried out in male hypertensives treated with atenolol, metoprolol, or bisoprolol. Compared with atenolol and metoprolol bisoprolol was found to be more effective and safe. The use of bisoprolol was associated with no negative changes and even with improvement of some parameters of sexual function. Sildenafil could be used for correction of male sexual dysfunction occurring during treatment with other beta-blockers.