[Pregnancy and labor in Turner's syndrome].

In recent years, thanks to the introduction of in vitro fertilization method in clinical practice, the possibility of having children with Turner syndrome has increased significantly. Due to pronounced congenital hypogonadism, pregnancy, and especially delivery, in these patients can only be against the background of correct and timely hormone replacement therapy, which creates the conditions for the maturation of an artificially created fertilized ovum implanted in the uterus. Management of such patients before delivery requires a detailed selection of adequate therapy, which leads to gestation and even makes it possible to breastfeed a child. We give the medical history of one of our patient.

[Comparative analysis of fertile and infertile cycles during stimulation of ovulation with pergonal in patients with hypo- gonadotropic amenorrhea]. / Sravnite'lnyi analiz ferti'lnykh i neferti'lnykh tsiklov pri stimuliatsii ovuliatsii pergonalom u patsientok s gipogonado- tropnoi amenoreei.

A comparative assessment of variations in sex hormone levels and echographic parameters of fertile and infertile cycles was carried out in patients with gonadotrophic deficiency during pergonal induction of the ovulation. It was demonstrated that 83% of the infertile cycles were the first stimulation cycles. Basic differences were identified in the variation of sex hormone levels and echographic parameters of target organs between the fertile and infertile cycles. It is concluded that the first ovulation-induction course should be regarded as a preventive or preparatory one, where an optimum drug dosage is adjusted while the gonads and target organs are getting ready for the ovulation.

[Multiple correlation analysis of the ratio between the sex hormone content of the peripheral blood and follicular fluid and the size of the follicle]. / Mnozhestvennyi korreliatsionnyi analiz zavisimosti mezhdu soderzhaniem polovykh gormonov v perifericheskoi krovi i v follikuliarnoi zhidkosti i razmerami follikula.

A multiple correlative analysis of the relationship between the follicle size, steroid hormone concentration in the follicular fluid and their peripheral blood content during different stages of the follicle growth was performed. It was suggested that both the growth of dominant follicle and the change in steroid hormone concentration are non-linear processes. It was demonstrated that steroid hormone content in the peripheral blood reflects steroidogenic activity of the dominant follicle thecal tissue.