Scleral Graft and Muscle Transposition in the Treatment of Scleromalacia and Hypertropia Following Retinal Detachment Surgery.

Ocular motility disfunction and eye wall defects are possible complications of retinal detachment (RD) surgery that may interfere with an acceptable functional result. The case of a 41-year-old man that developed scleromalacia and hypertropia after an RD surgery is presented. A cadaveric scleral graft (CSG) was used for the treatment of scleromalacia. Because of absence of the anterior aspect of the inferior rectus muscle, an anterior transposition of the ipsilateral inferior oblique muscle (ATIIO) for the correction of hypertropia was performed in the same surgical procedure. After a follow-up of 22 months, a good evolution of CSG was observed, as well as orthotropia with the exception for extreme inferior gazes. CSG and ATIIO proved to be an effective initial treatment for scleromalacia and hypertropia secondary to RD surgery.

The cornea of Guinea pig: structural and functional studies.

OBJECTIVE: To describe the functional and structural characteristics of the cornea in healthy Guinea pigs. ANIMALS STUDIED: Healthy male and female pigmented and albino Guinea pigs (Caviaporcellus) aged 3-5 months old were used. PROCEDURES: The animals' corneas underwent different in vivo studies including: slit-lamp biomicroscopy, fluorescein staining (FS), break-up time test (BUT), confocal microscopy and pachymetry. The corneas were also studied histopathologically with light microscopy, immunohistochemistry and transmission electron microscopy. RESULTS: No significant differences were found between pigmented and albino animals, male and female, OD and OS in any study performed. The differences on corneal thickness values were not significant among central (227.85 +/- 14.09 microm) and upper and temporal peripheral regions (226.60 +/- 12.50 and 225.70 +/- 14.40 microm, respectively). All histological studies performed permitted identification and precise description of the different corneal structures in Guinea pigs: the stratified epithelium (45.52 +/- 5.26 microm), Bowman's layer (2.23 +/- 0.38 microm), stroma (163.69 +/- 4.90 microm), Descemet's membrane (3.96 +/- 0.46 microm) and the endothelium (5.09 +/- 0.71 microm). Combining results from all eyes mean and SD from corneal BUT values was 4.98 +/- 1.67 s. Corneas often showed discrete superficial erosions being the FS positive in both eyes from all the animals. CONCLUSION: This study provides a detailed in vivo and postfixed histological description of the Guinea pig's cornea and information about the physiological tests.