RESUMO
Dental carie is the most common infectious disease in humans. In the past decades, it has been described as a multifactorial condition, where diet and the immune response are main factors for the establishment of the disease. The authors approach the formation of the bacterian biofilm, the host's immune response, according to its maturation and deficiencies, and the current research to find a preventive intervention for this disease.
Assuntos
Cárie Dentária/imunologia , Cárie Dentária/prevenção & controle , Humanos , Mucosa Bucal/imunologiaRESUMO
The title mol-ecule, C(11)H(10)N(2)O(6), has a Z conformation about the C=N bond of the oxime unit. There are significant twists from planarity throughout the mol-ecule, the most significant being between the hydroxy-imino and ester groups which are effectively orthogonal with an N-C-C-O(carbon-yl) torsion angle of 91.4â (2)°. The crystal packing features oxime-benzoyl O-Hâ¯O contacts that lead to chains along [010] and C-Hâ¯O interactions also occur.