RESUMO
Twenty-five patients with immunologically classified B cell chronic lymphocytic leukaemia (CLL) were examined for skin lesions. Six showed evidence of cutaneous involvement, and histological examination of skin biopsies from these patients revealed perivascular lymphocytic infiltration with some diffuse involvement in three. Immunohistological analysis with a range of B and T cell specific monoclonal antibodies revealed that in all cases the infiltrate was predominantly T cell in origin and that epidermotropism in three cases was also associated with T cell components. Six control patients with macroscopically normal skin were also biopsied and these biopsies subjected to the same assessment. All were normal.
Assuntos
Leucemia Linfoide/patologia , Pele/patologia , Linfócitos B/imunologia , Humanos , Leucemia Linfoide/imunologia , Pele/imunologia , Linfócitos T/imunologiaAssuntos
Verrugas/terapia , Adulto , Criança , Humanos , Neoplasias Cutâneas/diagnóstico , Verrugas/diagnósticoAssuntos
Pele/efeitos da radiação , Raios Ultravioleta , Humanos , Micro-Ondas , Lesões por Radiação , Raios XRESUMO
The surface microtopography of normal human skin varies from one anatomical region to another. The patterns at different sites are considered to reflect different orientations of dermal fibers. A simple technique is described that enables such orientations to be accurately delineated. Various scars resulting from lacerations, surgical incisions, and steroid-induced striae were examined in the manner described.
