Comparative evaluation of the efficacy of light amplification by the stimulated emission of radiation, desensitizing agents, and their combined effect on dentinal hypersensitivity in cuspids and bicuspids - In Vivo Study.

Context: Dentinal Hypersensitivity is the most common dental problem, in order to find a suitable treatment plan this study was conducted incorporating LASER and desensitizing agents on the patients complaining of dentinal hypersensitivity in cuspids and bicuspids. Most of the desensitizing agents provided incomplete relief hence the combination of LASER and Desensitizing agents proved to be successful. Aim: The aim of this study is to evaluate and compare the efficacy of individual desensitizing agents and c (LASER) and also to know their potential in reducing dentinal hypersensitivity when both desensitizing agents and LASER are combined together and applied on cuspids and bicuspids. Setting and Design: Sixty patients with sensitivity only in cuspids and bicuspids and not having caries, restoration, or undergoing any desensitizing therapy were selected. Patients were divided into 5 groups with 12 patients in each group. Materials and Methods: Air blast stimulus was given for 10 s from 1 cm distance on the affected group. Verbal analog score was recorded. Treatment was carried on according to the groups mentioned: Group I - nanohydroxyapatite was applied for 15 min; Group II - biosilicate was applied for 15 min; Group III - LASER application was done twice for 60 s in noncontact mode; Group IV - Nanohydroxyapatite plus LASER application; and Group V - biosilicate plus LASER application. Desensitizing agent was applied with the applicator tip and was left for 15 min. It was then rinsed and again the stimulus was given, and the score was recorded. The same treatment procedure was repeated on 1st, 7th, and 14th day and the score was recorded and analyzed using ANOVA. Results: The maximum reduction in sensitivity score was observed in patients where nanohydroxyapatite and LASER application was done. Conclusion: All the investigated treatments have promising desensitizing potential, but maximum was found in Group IV > Group V > Group III > Group I > Group II.

Effect of three newer generation rotary files on smear layer removal using fumaric acid as an irrigant: A SEM study.

Background: To evaluate the efficacy of the smear layer removal with Fumaric acid when used in combination with new generation files Hyflex Electrical Discharge Machining (HEDM) file, Neoendo file, and Blueflex file. Materials and Methods: Sixty extracted mandibular premolars with single-canal were selected for this study. Radiographs were taken to confirm the presence of single canal and absence of any type of calcifications, resorption, cracks, and fractures. The teeth were decoronated to a standardized length of 12 mm and working length was determined with ISO #15 K file. After this, teeth were randomly divided into 2 main groups - Control and Experimental group. In Control group, root canal instrumentation was performed with Neoendo, Blueflex, and HEDM files, respectively, along with 1 ml of 17% ethylenediaminetetraacetic acid (EDTA), and in Experimental group, root canal instrumentation was performed with Neoendo, Blueflex, and HEDM files, respectively, along with 1 ml of 0.7% fumaric acid for 1 min. Longitudinal grooves were prepared with slow-speed silicon carbide disc on the buccal and lingual surfaces of each root. Preparation for scanning electron microscope was done and phototmicrographs at ×3000 were taken. Statistical Analysis: The results were analyzed using ANOVA test for comparison of smear layer scores among various groups and Tukey's HSD test was used for paired comparisons of total smear layer scores. Conclusions: On the basis of the present study, Blue flex file along with fumaric acid was found to be best among the groups and Neo endo along with EDTA was the poorest.

Comparative analysis of platelet-rich fibrin, platelet-rich fibrin with hydroxyapatite and platelet-rich fibrin with alendronate in bone regeneration: A cone-beam computed tomography analysis.

AIM: This clinical study was designed to evaluate the volumetric healing of periapical (PA) bone defect after PA surgery, using platelet-rich fibrin (PRF), and its combination with hydroxyapatite and alendronate. SUBJECTS AND METHODS: Twenty male patients of age between 25 and 35 years, having PA pathology (>5 mm on intraoral periapical radiograph (IOPA)) with intraoral sinus opening, were included in this study. Cone-beam computed tomography (CBCT) imaging of all patients was done. Root canal treatment with PA surgery was done. Patients were divided into four groups (5 in each group), on the basis of material placed in PA bone defect. After 1 year, CBCT imaging was done. Linear measurement of maximal dimensions in all three orthogonal planes was done in both pre- and post-CBCT image. These measurements were used to estimate the volume of the lesion healed after 1 year of surgery. STATISTICAL ANALYSIS: Analysis of variance and Post hoc Tukey's test were used for statistical analysis. RESULTS: Change in volume were significantly different between Group 1 vs Group 3; Group 2 vs Group 3 and Group 3 vs Group 4. The Group Order for change in volume 1 year post surgery Group 3> Group 4 ≈ Group 2> Group 1. CONCLUSIONS: PA bone healing after surgery is enhanced by placing combination of bone regenerative materials. PRF with hydroxyapatite provides best healing outcomes in comparison to PRF with alendronate or PRF alone.

Comparative analysis of smear layer removal by conventional endodontic irrigants with a newly experimented irrigant-fumaric acid: A scanning electron microscopic study.

INTRODUCTION: This study was aimed to evaluate the efficacy of 17% ethylenediaminetetraacetate (EDTA), 7% maleic acid and 0.7% fumaric acid in smear layer removal from the root canal walls. MATERIALS AND METHODS: Forty single-rooted mandibular premolars were collected and prepared till F3 rotary ProTaper file with 1 ml of 3% of sodium hypochlorite after each instrument change. Samples were randomly divided into 4 groups according to the final irrigating solution: 17% EDTA, 7% maleic acid, 0.7% fumaric acid, and 0.9% saline. The samples were prepared for scanning electron microscope analysis to observe smear layer removal at coronal, middle, and apical third level of root canal system. RESULTS: At coronal third level, fumaric acid was equally efficient in smear layer removal when compared to maleic acid and EDTA without any significant difference between them. At the middle third, fumaric acid showed significantly better results than maleic acid followed by EDTA. At the apical third, both fumaric acid and maleic acid were equally effective without any significant difference between them but both showed significantly better results than EDTA. CONCLUSION: Fumaric acid can be tried as a new irrigating agent for smear layer removal in root canal system.

Evaluation of fracture resistance of endodontically treated teeth restored with composite resin along with fibre insertion in different positions in vitro.

This study was carried out to compare the different techniques of placement of polyethylene fibre (Ribbond) on reinforcement of endodontically treated teeth with MOD cavities in vitro. Forty extracted human premolars were randomly assigned to four groups (n = 10). Teeth in Groups I-IV received root canal treatment and a MOD cavity preparation, with gingival cavosurface margin 1.5 mm in coronal to cementoenamel junction. Group I served as no fibre group, Group II as occlusal fibre group, Group III as base fibre group and Group IV as dual-fibre group (occlusal and base both). Subsequent to restoring with composite resin and thermocycling, a vertical compressive force was applied at a cross-head speed of 0.5 mm min(-1) using universal testing machine until fracture. Data were analysed using one-way analysis of variance and Tukey's post hoc tests. Fracture resistance was significantly highest in dual-fibre group (P < 0.001) as compared with other groups. The highest favourable fracture rate was observed in the base fibre group (70%). This study concluded that the use of polyethylene fibre inserted over or under the restoration significantly increased the fracture strength of the root canal-treated teeth and maximum fracture resistance was observed when cavity was restored using dual-fibre technique.