RESUMO
Rift Valley fever (RVF) is a zoonotic viral disease caused by the RVF phlebovirus (RVFV) that infects a variety of animal species including sheep and goats. Sera (n = 893) collected between 2013 and 2015 from randomly selected indigenous sheep and goats in seven provinces of the Democratic Republic of the Congo (DRC) were tested for the presence of specific immunoglobulin G (IgG) and M (IgM) against RVFV, using two commercially available enzyme-linked immunosorbent assays. The reverse transcription polymerase chain reaction (RT-PCR) was also used to detect RVFV nucleic acid. There was significant variation in true seroprevalence of RVFV for both sheep and goats between the seven provinces investigated. Values ranged from 0.0 (95% confidence interval [CI] 0.0-6.55) to 23.81 (95% CI 12.03-41.76) for goat and 0.0 (95% CI 0.0-7.56) to 37.11 (95% CI 15.48-65.94) for sheep, respectively. One serum (1.85%) out of 54 that tested positive for IgG was found to be IgM-positive. This same sample was also positive by RT-PCR indicating an active or recent infection. These findings report the presence of RVFV in small ruminants in the DRC for the first time and indicate variations in exposure to the virus in different parts of the country.
Assuntos
Doenças das Cabras/epidemiologia , Febre do Vale de Rift/epidemiologia , Vírus da Febre do Vale do Rift/isolamento & purificação , Doenças dos Ovinos/epidemiologia , Animais , República Democrática do Congo/epidemiologia , Ensaio de Imunoadsorção Enzimática/veterinária , Feminino , Doenças das Cabras/virologia , Cabras , Imunoglobulina G/imunologia , Imunoglobulina M/imunologia , Masculino , Prevalência , Reação em Cadeia da Polimerase Via Transcriptase Reversa/veterinária , Febre do Vale de Rift/virologia , Estudos Soroepidemiológicos , Ovinos , Doenças dos Ovinos/virologiaRESUMO
In 2017, highly pathogenic avian influenza A(H5N8) virus was detected in poultry in the Democratic Republic of the Congo. Whole-genome phylogeny showed the virus clustered with H5N8 clade 2.3.4.4B strains from birds in central and southern Asia. Emergence of this virus in central Africa represents a threat for animal health and food security.
