RESUMO
We carried out a retrospective descriptive study to determine prevalence and risk factors for tardive dyskinesia (TD) among psychotic patients treated with conventional neuroleptics in 4 centres in Saudi Arabia. Records of patients who had been taking > or = 1 conventional neuroleptic for > or = 6 months from January 1997 to December 2000 were examined; 151 patients were included in the final analysis. Only 51 had TD; another 59 (6.8%) patients had drug-induced Parkinson disease. Duration of treatment (P < 0.001), higher doses of neuroleptics (P < 0.01) and age over 40 years (P < 0.01) were associated with TD. A statistically significant difference in prevalence was found between Arabs (23.5%) and Afro-Arabs (45.5%) (P < 0.01). Overall prevalence of TD among psychotic patients was 5.9%.
Assuntos
Antipsicóticos/efeitos adversos , Árabes/estatística & dados numéricos , Discinesia Induzida por Medicamentos/epidemiologia , Discinesia Induzida por Medicamentos/etiologia , Transtornos Psicóticos/tratamento farmacológico , Adulto , África/etnologia , Distribuição por Idade , População Negra/estatística & dados numéricos , Clorpromazina/efeitos adversos , Estudos Transversais , Discinesia Induzida por Medicamentos/diagnóstico , Feminino , Haloperidol/efeitos adversos , Humanos , Masculino , Vigilância da População , Prevalência , Estudos Retrospectivos , Fatores de Risco , Arábia Saudita/epidemiologia , Distribuição por Sexo , Fatores Socioeconômicos , Fatores de Tempo , Trifluoperazina/efeitos adversosRESUMO
We carried out a retrospective descriptive study to determine prevalence and risk factors for tardive dyskinesia [TD] among psychotic patients treated with conventional neuroleptics in 4 centres in Saudi Arabia. Records of patients who had been taking </=1 conventional neuroleptic for </= 6 months from January 1997 to December 2000 were examined; 151 patients were included in the final analysis. Only 51 had TD; another 59 [6.8%] patients had drug-induced Parkinson disease. Duration of treatment [P < 0.001], higher doses of neuroleptics [P < 0.01] and age over 40 years [P < 0.01] were associated with TD. A statistically significant difference in prevalence was found between Arabs [23.5%] and Afro-Arabs [45.5%] [P < 0.01]. Overall prevalence of TD among psychotic patients was 5.9%
