RESUMO
Renal cholesteatoma is an extremely uncommon disease. The renal pelvis is the most common site, but the lesion can be localized, even if rarely, in a calix or in the ureter. Histologically it consists of a keratinizing desquamative squamous metaplasia, with absence of cellular atypia in the urothelium, therefore cholesteatoma is not considered as a premalignant lesion. Authors report a case of renal cholesteatoma and take into consideration particularly the question regarding the diagnostic approach, that in spite of the help of new imaging techniques, as TC, is unable to arrive at a certain diagnosis, and the therapeutic approach, that must be conservative, when it's possible and according to the majority of Authors.
Assuntos
Colesteatoma , Nefropatias , Colesteatoma/diagnóstico , Colesteatoma/etiologia , Colesteatoma/cirurgia , Diagnóstico por Imagem , Humanos , Nefropatias/diagnóstico , Nefropatias/etiologia , Nefropatias/cirurgia , Masculino , Pessoa de Meia-Idade , Nefrectomia , Complicações Pós-Operatórias , Tuberculoma/complicações , Tuberculose Renal/complicações , Tuberculose Renal/cirurgia , Derivação UrináriaRESUMO
The epidermoid cyst of the testis represents about 1% of all testicle tumours. The average age of presentation ranges from the second and the fourth decade of life. Its clinical features do not differ from those of a testis malignancy. Preliminary clinical and laboratory findings do not determine the diagnosis. The Authors report a case and review the Literature (about 150 cases up to 1985). Therapeutic strategy is also discussed: orchiectomy or simple removal of the cyst.
Assuntos
Cisto Epidérmico/cirurgia , Doenças Testiculares/cirurgia , Adolescente , Humanos , MasculinoRESUMO
This study was carried out to evaluate the metabolic consequences of osteosclerotic skeletal metastases of prostatic origin in a homogeneous group of patients. We found significantly increased mean values of serum alkaline phosphatase activity and significantly reduced mean values of serum phosphate, 24-h urinary calcium, fasting calcium excretion and TmP/GFR in cancer patients with respect to age-matched controls. Mean serum immunoreactive parathyroid hormone (iPTH) levels were raised, with two patients showing increased values of the hormone above our normal limits. Our findings indicate that mild secondary hyperparathyroidism is a feature of these patients. However, it cannot be excluded that both the reduced serum phosphate and TmP/GFR values may be related, at least in some cases, to the effects of the tumour itself on tubular reabsorption of phosphate.
