1.
Klin Lab Diagn
; (1): 17-20, 2008 Jan.
Artigo
em Russo
| MEDLINE
| ID: mdl-18314774
RESUMO
Multiple myeloma is a malignant proliferative disease of plasma cells. Flow cytometric immunophenotyping makes it possible to identify a malignant clone of myeloma cells in the shortest possible time, to determine its phenotype, and differentiate transformed and preserved plasma cells. The article presents an immunophenotyping strategy using three-color monoclonal antibodies (CD35, CD14, CD38, CD138, and CD19) and an algorithm of verification of transformed plasma cells. Particular emphasis is placed on both the practical aspects of performing this assay and on the clinical application of the obtained results.
Assuntos
Antígenos CD/análise , Medula Óssea/imunologia , Imunofenotipagem/métodos , Mieloma Múltiplo/diagnóstico , Anticorpos Monoclonais/imunologia , Medula Óssea/patologia , Citometria de Fluxo/métodos , Humanos , Mieloma Múltiplo/patologia
2.
Vopr Okhr Materin Det
; 23(10): 65-6, 1978 Oct.
Artigo
em Russo
| MEDLINE
| ID: mdl-706277