[Effect of gastric bypass on the cardiovascular risk and quality of life in morbid obese patients]. / Efecto del bypass gástrico sobre el riesgo cardiovascular y la calidad de vida en pacientes con obesidad mórbida.

OBJECTIVES: To determine the prevalence of major comorbidities of morbidity obese patients and to evaluate the gastric bypass effect on the weight status, cardiovascular risk and quality of life in these patients. METHODS: The evolution of weight, comorbidity, 10- year follow-up of cardiovascular risk (estimated by the Framingham risk score) and quality of life using the test BAROS (Bariatric Analysis and Reporting Outcome System) was analyzed in 162 patients with morbid obesity before and 2 years after gastric bypass. RESULTS: Body mass index (BMI) was reduced from 51.12 ± 7.22 to 29.94 ± 4.86 kg/m2 (72.85% loss of excess weight). Hypertension (HT), dyslipidemia and type 2 diabetes mellitus (T2DM) were resolved in 71.93%, 91.38% and 82.93% respectively (p < 0.001). Cardiovascular risk greater than 10% was reduced from 25.91% to 4.32% (p < 0.001). According to BAROS scale, surgery was positive in 95% of cases. CONCLUSIONS: Gastric bypass is very effective in weight loss; benefits in comorbidities, cardiovascular risk and quality of life.

Objetivos: Determinar la prevalencia de las principales comorbilidades asociadas a la obesidad mórbida y evaluar el efecto del bypass gástrico sobre el estado ponderal, riesgo cardiovascular y calidad de vida en estos pacientes. Métodos: Estudio descriptivo con medidas del cambio intrasujeto (antes-después) en una muestra de 162 pacientes de los resultados del bypass gástrico sobre la evolución ponderal, comorbilidades asociadas, riesgo cardiovascular a 10 años (estimado mediante las tablas de Framingham) y calidad de vida mediante el test BAROS (Bariatric Analysis and Reporting Outcome System). Resultados: El índice de masa corporal (IMC) se reduce de 51,12 ± 7,22 kg/m2 a 29,94 ± 4,86 kg/m2 (72,85% de sobrepeso perdido) y se resuelven la hipertensión arterial (HTA), la dislipemia y la diabetes mellitus tipo 2 (DMT2) en el 71,93%, 91,38% y 82,93% respectivamente (p < 0,001). El riesgo cardiovascular mayor del 10% se reduce del 25,91% al 4,32% (p < 0,001). Según la escala BAROS, el resultado de la cirugía fue favorable en el 95% de los casos. Conclusiones: La cirugía bariátrica mediante bypass gástrico demuestra ser muy efectiva para la reducción ponderal y comorbilidades asociadas, mejorando notablemente la calidad de vida.

[Anatomoclinical and diagnostic characteristics of thyroid carcinoma. Study of 126 cases]. / Características anatomoclínicas y diagnósticas del carcinoma tiroideo. Estudio de 126 casos.

A retrospective review was conducted among 126 patients treated for thyroidal carcinoma--86 papillary, 31 follicular, 4 anaplastic, 1 lymphoma, and 4 non-familiar medullary--in our area between 1979 and 1992. Diagnostic and clinical findings obtained were evaluated along with those from physical examinations, imaging techniques (i.e., echography and gamma spectrometry), and histological study (i.e., fine needle puncture-aspiration and intra-operatory biopsy). The majority (88 cases) presented a hard node or one of elastic consistency, while in 34 cases, there was a diffuse or nodular increase. Only four patients manifested a normal thyroid in the physical examination. A 2.4% had a normal gammagraphy, 70% presented a cold node, 1.6% an alient node, and there was evidence of heterogeneous uptake in 23.7%. In the echography study, 63.3% were noted as being solid nodes, 11.4% as cysts, and 24% as mixed. The sensitivity of the fine needle puncture-aspiration was 76.4% and 66.6% for intraoperative biopsy.

Effect of vagotomy on the conjugated bile acids in the dog.

The effects of truncal vagotomy and selective gastric vagotomy on the conjugated bile acids and rations T/G and Tri/Di have been studied in twenty dogs. The results show that truncal vagotomy has no effect on the conjugated bile acid values determined in the 4th and 16th week. The ratio T/G increased while the Tri/Di decreased in the 16th week. The selective gastric vagotomy only shows a change of the taurocholic acid levels which are lower than the control levels in the 4th week.