Factores relacionados con las características alimentarias de niños de 6 a 36 meses detectadas a través de teleconsulta en Lambayeque- Perú / Factors related to the dietary characteristics of children aged 6 to 36 months detected through teleconsultation in Lambayeque- Peru

Fundamentos: Los primeros años de vida son períodos críticos para el ser humano, necesita de cuidadosbásicos que ayuden a optimizar el crecimiento y desarrollo al máximo. El objetivo fue determinar la relaciónde los factores sociodemográficos maternos y antropométricos de niños de 6 a 36 meses y las característicasalimentarias. Métodos: Estudio correlacional, transversal, con 60 madres de niños de 6 a 36 meses. Los datos serecogieron utilizando el recordatorio de 24 horas. Resultados: Hubo relación significativa moderada entre la edad del niño con el consumo de lácteos (p=0,006,v=0,400), huevo (p=0,009, v=0,362) y lactancia materna continuada (p=0,000, v=0,514), relación significativamoderada entre el P/T y consumo de verduras (p=0.026, v=0,312), relación significativa baja entre residenciade la madre y frecuencia adecuada de comida (f=0,029, v=0,299), relación significativa moderada entre elnivel de instrucción con la cantidad de alimentos ( 2=5.701, p=0,017, v=0, 308). Conclusiones: Los niños consumieron diversos tipos de alimentos: frutas, cereales, carnes, derivados lácteosy lactancia materna continuada, con ingesta de proteínas y lípidos superior a lo recomendado. El grado deinstrucción influye en la calidad de alimentación complementaria. Es indispensable programas de capacitaciónpermanente en alimentación responsiva y saludable utilizando medios informativos virtuales y presenciales. (AU)

Background: The first years of life are considered a critical period for the human being, requiring basic carethat helps optimize growth and development to the maximum. The objective of the study was to determinethe relationship between maternal sociodemographic and anthropometric factors of children aged 6 to 36months and dietary characteristics. Methods: A descriptive, cross-sectional study was carried out in 60 mothers of children aged 6 to 36 months.Data was collected through the 24-hour recall. Results: There was a significant relationship between the age of the child with the consumption of dairyproducts (p=0.006, v=0.400), eggs (p=0.009, v=0.362) and continued breastfeeding (p=0.000, v=0.514),moderate significant relationship between weight/height and vegetable consumption (p=0.026, v=0.312), lowsignificant relationship between mother's residence and adequate meal frequency (f=0.029, v=0.299),significant relationship moderate between the level of instruction with the amount of food (X2=5.701,p=0.017, v=0.308). Conclusions: The mother's residence and educational level seem to be related to the frequency of food, theconsumption of meat and the amount of food. Of the child, age and height with egg consumption; age withdairy consumption, daily feeding frequency, continued breastfeeding, weight/height of the child withvegetable consumption. (AU)

Efecto de una intervención de teleenfermería en contexto pandemia para prevenir anemia infantil: estudio piloto en lambayeque, perú

Objetivo: Evaluar el efecto de una intervención de teleenfermería en contexto de pandemia para prevenir la anemia infantil en Perú. Material y Método: Estudio piloto, analítico, cuasi experimental con pre y pos-test. La muestra estuvo constituida por 60 madres de un establecimiento de atención primaria de Lambayeque, Perú, que fueron seleccionadas a conveniencia y luego asignadas al Grupo control (30) y Grupo experimental (30), este último sometido a una intervención de teleenfermería de 4 meses. El efecto se midió comparando el promedio de hemoglobina e ingesta alimentaria de hierro antes y después de la intervención. La hemoglobina fue determinada bioquímicamente a través del análisis de sangre; la ingesta alimentaria de hierro fue recogida mediante entrevistas telefónicas a través del recordatorio de 24 horas. Resultados: El promedio de hemoglobina en el grupo experimental no presentó diferencia significativa entre el inicio y el final de la intervención (p= 0,199); en el grupo control el promedio de hemoglobina presentó diferencias significativas entre el inicio y el final de la intervención (p= 0,013). El promedio de ingesta alimentaria de hierro en los niños del grupo control (p= 0,049) y experimental (p= 0,000) sí tuvieron diferencias significativas entre el inicio y el final de la intervención. Conclusión: Los niños que recibieron la intervención con teleenfermería se mantuvieron sin anemia y la ingesta alimentaria de hierro aumentó por lo que se corrobora que los programas de teleenfermería tienen el potencial de incrementar información sobre alimentación, favoreciendo la salud del niño, de la madre y la familia.

Objective: To evaluate the effect of a telenursing intervention in the context of the pandemic to prevent childhood anemia in Peru. Material and Method: Pilot, analytical, quasi-experimental study with pre- and post-test. The sample consisted of 60 mothers from a primary health care facility in Lambayeque, Peru, who were selected at convenience and then assigned to a control group (30) and an experimental group (30), with the latter being subjected to a 4 months telenursing intervention. The effect was measured by comparing the average hemoglobin and dietary iron intake before and after the intervention. Hemoglobin level was determined biochemically through blood analysis. Dietary iron intake was collected through telephone interviews following a 24-hour recall. Results: The average hemoglobin level in the experimental group did not show significant differences between the beginning and the end of the intervention (p= 0.199); whereas in the control group, the average hemoglobin level showed significant differences between the beginning and the end of the intervention (p= 0.013). The average dietary intake of iron among the children of the control group (p= 0.049) and the experimental group (p= 0.000) had a significant difference between the beginning and the end of the intervention. Conclusion: The children who received the telenursing intervention suffered no anemia and the dietary iron intake increased, thus corroborating that telenursing programs have the potential of offering more information on nutrition, favoring the health of the child, the mother and the family.

Objetivo: Avaliar o efeito de uma intervenção de telenfermagem no contexto da pandemia para prevenir a anemia infantil no Peru. Material e Método: Estudo piloto, analítico, quase-experimental com pré e pós-teste. A amostra foi composta por 60 mães de uma unidade básica de saúde de Lambayeque, Peru, que foram selecionadas por conveniência e depois designadas para um dos dois grupos de pesquisa: grupo controle=30 e um grupo experimental=30, submetido esse último a uma intervenção de telenfermagem de 4 meses. O efeito foi medido comparando a hemoglobina média e a ingestão de ferro dietético antes e depois da intervenção. O nível de hemoglobina foi determinado bioquimicamente através da análise de sangue. A ingestão de ferro dietético foi coletada através de entrevistas telefónicas por meio de um recordátorio de 24 horas. Resultados: O nível médio de hemoglobina no grupo experimental não apresentou diferenças significativas entre o início e o final da intervenção (p= 0,199). No grupo controle, a hemoglobina média mostrou diferenças significativas entre o início e o final da intervenção (p= 0,013). A ingestão alimentar média de ferro entre as crianças do grupo controle (p = 0,049) e do grupo experimental (p = 0,000) teve uma diferença significativa entre o início e o final da intervenção. Conclusão: As crianças que receberam a intervenção de teleenfermagem não sofreram anemia e a ingestão de ferro por via alimentar aumentou, corroborando assim que os programas de teleenfermagem podem oferecer mais informações sobre a nutrição, favorecendo a saúde da criança, da mãe e da família.

Post-bone-marrow-transplant leukemia cutis.

Granulocytic sarcoma or chloroma is a tumor of immature cells from the granulocyte line that is generally associated with acute myeloid leukemia. The skin is one of the most affected organs. This lesion may complicate hematological dyscrasias, which is generally indicative of a poor prognosis. We present a case of a 51-year-old patient who was diagnosed with acute myeloid leukemia with a complex karyotype that debuted with a post-transplant cutaneous and hematological relapse, a very rare occurrence in the literature given that no extramedullary involvement was present prior to the transplant.

A 48 SNP set for grapevine cultivar identification.

BACKGROUND: Rapid and consistent genotyping is an important requirement for cultivar identification in many crop species. Among them grapevine cultivars have been the subject of multiple studies given the large number of synonyms and homonyms generated during many centuries of vegetative multiplication and exchange. Simple sequence repeat (SSR) markers have been preferred until now because of their high level of polymorphism, their codominant nature and their high profile repeatability. However, the rapid application of partial or complete genome sequencing approaches is identifying thousands of single nucleotide polymorphisms (SNP) that can be very useful for such purposes. Although SNP markers are bi-allelic, and therefore not as polymorphic as microsatellites, the high number of loci that can be multiplexed and the possibilities of automation as well as their highly repeatable results under any analytical procedure make them the future markers of choice for any type of genetic identification. RESULTS: We analyzed over 300 SNP in the genome of grapevine using a re-sequencing strategy in a selection of 11 genotypes. Among the identified polymorphisms, we selected 48 SNP spread across all grapevine chromosomes with allele frequencies balanced enough as to provide sufficient information content for genetic identification in grapevine allowing for good genotyping success rate. Marker stability was tested in repeated analyses of a selected group of cultivars obtained worldwide to demonstrate their usefulness in genetic identification. CONCLUSIONS: We have selected a set of 48 stable SNP markers with a high discrimination power and a uniform genome distribution (2-3 markers/chromosome), which is proposed as a standard set for grapevine (Vitis vinifera L.) genotyping. Any previous problems derived from microsatellite allele confusion between labs or the need to run reference cultivars to identify allele sizes disappear using this type of marker. Furthermore, because SNP markers are bi-allelic, allele identification and genotype naming are extremely simple and genotypes obtained with different equipments and by different laboratories are always fully comparable.

Rosetoid schwannoma (neuroblastoma-like) in association with an anetoderma.

BACKGROUND: We report an additional case of an extremely uncommon but distinctive histological variant of benign schwannoma, which was previously designated as neuroblastoma-like schwannoma by Goldblum et al. METHODS: A 29-year-old woman referred to a 6-year-history of an atrofic macule. Its clinical appearance was similar to that of an anetoderma. RESULTS: A cutaneous biopsy showed findings consistent with a neuroblastoma-like schwannoma with the following peculiar features: (i) Being fully composed of rosette-like structures. (ii) Association to an anetoderma. CONCLUSIONS: Because neither the histological pattern nor the type of tumor allows a differential diagnosis with neuroblastoma, we propose the descriptive term of rosetoid schwannoma. And to our knowledge, this will be the first case reported of rosetoid schwannoma associated to anetoderma.

The expression of epidermal growth factor receptor results in a worse prognosis for patients with rectal cancer treated with preoperative radiotherapy: a multicenter, retrospective analysis.

BACKGROUND AND PURPOSE: Expression of epidermal growth factor receptor (EGFR) is observed in 50-70% of colorectal carcinoma and is associated with poor prognosis. The aim of this study was to determine the prognostic value of EGFR status before radiotherapy in a group of patients with locally advanced rectal cancer treated with preoperative radiotherapy. PATIENTS AND METHODS: Eighty-seven patients were studied retrospectively. Treatment consisted of pelvic radiotherapy, in 50 patients with concomitant chemotherapy and surgical resection. Immunohistochemistry for EGFR was determined at the preradiation biopsy and in the resected specimens. Immunohistochemical analysis for EGFR expression was evaluated according to extension and staining intensity. We defined positive staining (EGFR positive), when extension was 5% or more. RESULTS: A total of 52 of 87 tumors showed EGFR positive status at biopsy (60%) and EGFR expression was associated neither with clinical tumor stage nor with clinical nodal stage. EGFR positive expression was linked to a lack of pathologic complete response to preoperative radiotherapy (P=0.006). Disease-free survival was lower among patients with EGFR positive status before radiotherapy (P=0.003). In a multivariate analysis EGFR expression at biopsy was a statistically significant predictor of disease-free survival, RR=2.88(1.1-7.8), P=0.036. CONCLUSIONS: EGFR is expressed in a significant number of rectal tumors. EGFR-positive expression before radiotherapy is an indicator for poor response and low disease-free survival.