Biomecânica da córnea após laser de femtossegundo na cirurgia de catarata / Changes of corneal biomechanical after femtosecond laser–assisted for cataract surgery

Objetivo:Avaliar as alterações da biomecânica da córnea após laser de femtosegundo na cirurgia de catarata e comparar os parâmetros biomecânicos derivados do Corvis ST (Oculus Corvis ST, Scheimpflug Technology; Wetzlar, Germany) entre as técnicas do laser de femtossegundo e a facoemulsificação convencional após a cirurgia de catarata.Métodos:Estudo observacional, prospectivo envolvendo 151 olhos de 127 pacientes com diagnóstico de catarata nuclear. Setenta olhos de 65 pacientes foram submetidos à técnica do laser de femtossegundo (Alcon LenSx, Aliso Viejo,USA) e 76 olhos de 62 pacientes por meio da facoemulsificação convencional (Alcon Infinit, Fort Worth, USA). O sistema de tonometria de não contato integrado com a câmera ultrarrápida de Scheimpflug (Oculus Corvis ST, Scheimpflug Technology; Wetzlar, Germany) foi utilizado para avaliação da biomecânica da córnea antes e após a cirurgia de catarata pelas técnicas do laser de femtossegundo e a facoemulsificação convencional. Os parâmetros biomecânicos utilizados foram: deformidade de amplitude (DA), pressão intraocular, 1st A time, tempo de concavidade máxima, 2nd A time, 1st A Length, 2nd A Length, raio de curvatura de maior alcance, raio de curvatura normal, velocidade de entrada (Vin) e de saída (Vout). A densitometria do cristalino (scattering) através do PNS (Pentacam Nucleus Staging) foi realizado pela tomografia de córnea e segmento anterior (Pentacam® – Oculus, Wetzlar, Germany) em todos os pacientes para diagnóstico objetivo da opacidade do cristalino. Os critérios de exclusão foram: doença corneana, doenças da retina e/ou nervo óptico e cirurgia ocular prévia. O teste de Kolmogorov-Smirnov foi utilizado para avaliar a distribuição normal. O teste de Wilcoxon e o test-T foram utilizados para avaliação entre o pré-operatório e o primeiro dia de pós-operatório (D1) nos grupos do laser de femtossegundo (LFS) e do faco convencional (FC), respectivamente. O teste de Mann-Whitney foi realizado para avaliar as diferenças dos parâmetros biomecânicos da córnea derivados do Corvis ST entre os dois grupos (LFS; FC) após a cirurgia de catarata (D1). Foi considerado como estatisticamente significante p ≤ 0,05%.Resultados:A média de idade dos pacientes do grupo do LFS foi de 67,6 anos (± 9,9) e do grupo do FC foi de 68,4 anos (± 11,8).A média do PNS entre todos os pacientes (análise objetiva do cristalino) foi de 0,62 (± 0,67). No grupo do LFS, 9 dos 11 parâmetros foram estatisticamente significativos entre o Pré e D1; e no grupo do FC, 7 dos 11 parâmetros estudados foram estatisticamente significativos entre o Pré e D1. De todos os parâmetros biomecânicos derivados do Corvis ST estudados, somente o tempo de concavidade máxima da córnea (HC-time; p ≤ 0.0387) foi diferente entre os dois grupos (laser de femtossegundo x faco convencional) em D1.Conclusão:O laser de femtossegundo para cirurgia de catarata e a técnica de facoemulsificação convencional induziram alterações nas propriedades biomecânicas da córnea pelo Corvis ST no D1. Apenas 1 dos 11 parâmetros biomecânicos estudados foi diferente estatisticamente entre os grupos do LFS e FC.

Purpose:To evaluate the changes of corneal biomechanical after femtosecond laser – assisted cataract and to compare the parameters derived by Corvis ST between standard phacoemulsification and femtosecond laser – assisted in cataract surgeryMethods:This is a prospective study. 151 eyes of 127 patients were under went cataract surgery. 75 eyes of 65 patients were with femtosecond laser–assisted (FS)(Alcon Len Sx, Aliso Viejo,USA) and 76 eyes of 62 patients with standard phacoemulsification (SP) (Alcon Infinit, Fort Worth, USA). Lens scattering was evaluated using Scheimpflug Anterior Segment Tomography, using the new software PNS. The Scheimpflug images were taken with an ultra - high - speed camera during each measurement by the Corvis ST. The deformation amplitude (DA) and other parameters (e.g., pachyapex, intraocular pressure, 1st A time, highest concavity - time, 2nd A time, 1st A Length, 2nd A Length, curvature radius highest concavity, curvature radius normal, Vin, Vout) measured by the Corvis ST were studied in groups FLS and SP before an dafter cataract surgery. Exclusion criteria: corneal disease, retinal or optic nerves disease or previous ocular surgery. This is study analyzed was Kolmogorov-Smirnov for Normality. The Wilcoxon-test and t-test were utilized to evaluate the differences between pre and day 1in FS and SP, respectively. The Mann-Whitney test was used to compare the differences of parameters derived by Corvis ST - biomechanical properties between two groups (FS;SP). The p value less than 0.05 was considered statistically significant.Results:The mean age from patients of group FS was 67.6 y (± 9.9) and the group SP was 68.4 y (± 11.8). The mean PNS was 0.62 (±0.67). In group of FS, 9 of 11 parameters derived from Corvis ST were statisticall ysignificant (ss). In group of SP, 7 of 11 parameters derived from Corvis ST were ss. Only the HC - time was statistically significant between two groups (FS;SP) with p d” 0.0387.Conclusions:The use of the femtosecond laser – assisted system for cataract surgery and standard phacoemulsification induzed changes of biomechanical properties of the cornea by Corvis ST. Only 1 of 11 parameters studied was different statistically in two groups.

Ocular biomechanical metrics by CorVis ST in healthy Brazilian patients.

PURPOSE: To evaluate ocular biomechanical metrics given by the CorVis ST (Oculus, Inc., Berlin, Germany) in a population of healthy Brazilian patients. METHODS: An observational and cross-sectional study involving 1 eye randomly selected from 90 healthy patients. Studied parameters (including deformation amplitude, first applanation time, highest concavity time, second applanation time, first applanation length, second applanation length, curvature radius highest concavity, curvature radius normal, velocity in, and velocity out) derived from the CorVis ST were correlated to central corneal thickness from the Pentacam (Oculus, Inc.). Differences between data on the basis of gender were evaluated. RESULTS: Mean patient age was 35.80 ± 12.83 years (range: 21.07 to 78.84 years). Mean central corneal thickness was 547.50 ± 32.00 µm (range: 490 to 647 µm) and mean spherical equivalent refraction was -3.29 ± 3.69 diopters (range: -9.50 to +10.37 diopters). Mean deformation amplitude was 1.05 ± 0.08 mm (range: 0.91 to 1.26 mm). Highest concavity time was 18.38 ± 0.93 ms (range: 16.95 to 21.07 ms). Intraocular pressure was 16.43 ± 2.15 mm Hg (range: 11.50 to 21.0 mm Hg). First applanation time was 8.32 ± 0.33 ms (range: 7.53 to 9.12 ms) and second applanation time was 23.80 ± 0.44 ms (range: 22.76 to 24.95 ms). First applanation length (max) was 2.07 ± 0.38 mm (range: 1.20 to 3.10 mm) and second applanation length (max) was 2.37 ± 0.47 mm (range: 1.33 to 4.12 mm). Curvature radius highest concavity was 11.09 ± 2.06 mm (range: 7.58 to 15.98 mm) and curvature radius normal was 7.59 ± 0.67 mm (range: 6.82 to 11.02 mm). Velocity in was 0.21 ± 0.05 m/s (range: 0.16 to 0.72 m/s) and velocity out was -0.33 ± 0.07 m/s (range: -0.72 to -0.20 m/s). Studied parameters were not associated with gender. CONCLUSIONS: Eight of 11 ocular biomechanical metrics given by the CorVis ST were associated with central corneal thickness, but the influence of central corneal thickness on these measurements was low.

Effects of age on corneal deformation by non-contact tonometry integrated with an ultra-high-speed (UHS) Scheimpflug camera.

PURPOSE: To correlate parameters derived from corneal deformation resulting from non-contact tonometry integrated with an ultra-high-speed (UHS) Scheimpflug camera (Oculus Corvis ST, Scheimpflug Technology; Wetzlar, Germany) with age in normal eyes from young patients. METHODS: Observational, retrospective study involving one eye randomly selected from study participants, totaling 89 healthy eyes. The Scheimpflug images were taken with an ultra-high-speed camera during each measurement by the corvis ST. The deformation amplitude (DA) and other parameters (e.g., pachy apex, intraocular pressure, 1(st) A time, highest concavity-time, 2(nd) A time, 1(st) A Length, 2(nd) A Length, Wing-Dist, curvature radius highest concavity, curvature radius normal, Vin, Vout) measured by the corvis ST were correlated with age. The Kolmogorov-Smirnov test was applied, and Spearman's correlation test was utilized to evaluate the parameters measured by the Corvis ST and age. RESULTS: Mean patient age was 27.50 ± 6.30 years. The highest concavity-time was the only studied parameter statistically significantly correlated to age (i.e., p=0.04, rs=0.18). All other corvis parameters were not correlated to age. This included DA (p=0.319), intraocular pressure (p=0.854), pachy apex (p=0.066), 1(st) A time (p=0.959), 2(nd) A time (p=0.561), 1(st) Length (0.552), 2nd Length (p=0.697), Wing-Dist (p=0.769), curvature radius HC (p=0.145), curvature radius normal (p=0.513), Vin (p=0.980) and Vout (p=0.592). CONCLUSIONS: In healthy eyes, age and pressure or biomechanics as derived from the Corvis ST parameters were not associated with exception to highest concavity-time, i.e., the time from starting until the highest concavity is reached.

Effects of age on corneal deformation by non-contact tonometry integrated with an ultra-high-speed (UHS) Scheimpflug camera / Efeitos da idade sobre a deformação da córnea utilizando o sistema de tonometria de não contato com a câmera de Scheimpflug

PURPOSE: To correlate parameters derived from corneal deformation resulting from non-contact tonometry integrated with an ultra-high-speed (UHS) Scheimpflug camera (Oculus Corvis ST, Scheimpflug Technology; Wetzlar, Germany) with age in normal eyes from young patients. METHODS: Observational, retrospective study involving one eye randomly selected from study participants, totaling 89 healthy eyes. The Scheimpflug images were taken with an ultra-high-speed camera during each measurement by the corvis ST. The deformation amplitude (DA) and other parameters (e.g., pachy apex, intraocular pressure, 1st A time, highest concavity-time, 2nd A time, 1st A Length, 2nd A Length, Wing-Dist, curvature radius highest concavity, curvature radius normal, Vin, Vout) measured by the corvis ST were correlated with age. The Kolmogorov-Smirnov test was applied, and Spearman's correlation test was utilized to evaluate the parameters measured by the Corvis ST and age. RESULTS: Mean patient age was 27.50 ± 6.30 years. The highest concavity-time was the only studied parameter statistically significantly correlated to age (i.e., p=0.04, rs=0.18). All other corvis parameters were not correlated to age. This included DA (p=0.319), intraocular pressure (p=0.854), pachy apex (p=0.066), 1st A time (p=0.959), 2nd A time (p=0.561), 1st Length (0.552), 2nd Length (p=0.697), Wing-Dist (p=0.769), curvature radius HC (p=0.145), curvature radius normal (p=0.513), Vin (p=0.980) and Vout (p=0.592). CONCLUSIONS: In healthy eyes, age and pressure or biomechanics as derived from the Corvis ST parameters were not associated with exception to highest concavity-time, i.e., the time from starting until the highest concavity is reached.

OBJETIVO: Correlacionar os parâmetros derivados da deformação da córnea pelo sistema de tonometria de não-contato integrado com a câmera ultra-rápida de Scheimpflug (Oculus Corvis ST, Scheimpflug Technology; Wetzlar, Germany) com a idade de pacientes jovens saudáveis. MÉTODOS: Estudo observacional, retrospectivo envolvendo 89 olhos de 89 pacientes. As imagens de Scheimpflug foram feitas pela câmera acoplada ao sistema de tonometria de não-contato (Corvis ST) em cada paciente e os parâmetros utilizados foram: Deformidade de amplitude (DA), paquimetria, pressão intraocular, 1st A time, tempo de concavidade máxima, 2nd A time, 1st A Length, 2nd A Length, Wing-Dist, raio de curvatura de maior alcance, raio de curvatura normal, Velocidade de entrada (Vin) e de saída (Vout). Estes parâmetros foram correlacionados com a idade. RESULTADOS: A média de idade dos pacientes foi de 27,50 ± 6,30 anos. O tempo de concavidade máxima alcançada da córnea (HC-time) foi o único parâmetro estudado estatisticamente significante correlacionado com a idade (p=0,04, rs=0,18). O valor p das correlações dos parâmetros derivados do Corvis ST e idade foram: DA (p=0,319), pressão intraocular (p=0,854), paquimetria (p=0,066), 1st A time (p=0,959), 2nd A time (p=0,561), 1st Length (0,552), 2nd Length (p=0,697), Wing-Dist (p=0,769), raio de curvatura de maior alcance (p=0,145), curvature radius normal (p=0,513), Vin (p=0,980) e Vout (p=0,592). CONCLUSÃO: Em olhos saudáveis de pacientes jovens, a idade e os parâmetros pressóricos e biomecânicos da deformação da córnea não foram associados, exceto o tempo de concavidade máxima, que é o tempo do início de aplanação até a concavidade máxima alcançada da córnea.

Correlações entre straylight, aberrometria, opacidade e densitometria do cristalino em pacientes com catarata / Correlations of straylight, aberrometry, and lens scattering in cataract patients

Objetico: Correlacionar os níveis de straylight, de scattering, de opacidade do cristalino (LOCS III) e das aberrações ópticas intraoculares em pacientes com catarata nuclear. Métodos: Estudo observacional, prospectivo envolvendo 30 olhos de 30 pacientes com diagnóstico de catarata nuclear. A avaliação do straylight (espalhamento de luz) através do Log(s) foi realizada pelo C-Quant (Oculus, Wetzlar, Germany). A densitometria do cristalino (scattering) através do PNS (Pentacam Nucleus Staging) foi realizada pela tomografia de córnea e segmento anterior (Pentacam® - Oculus, Wetzlar, Germany) e a análise do tipo e graduação da opacidade do cristalino foi feito pelo Lens Opacities Classification System (LOCS III). O Ray tracing (iTrace, Vista, Tracy Technologies) foi utilizado para avaliação da aberrometria total e intraocular onde foi calculado com a integração da Topografia de Plácido. Os critérios de exclusão foram: doença corneana, doenças da retina e/ou nervo óptico e cirurgia ocular prévia. O Teste de Kolmogorov-Smirnov foi utilizado para avaliar a distribuição normal e o Teste de Spearman (não paramétrico) utilizado para as correlações entre as variáveis Log(s) x PNS; Log(s) x LOCS III; LOCS III x PNS; RMS IO x PNS; RMS IO x LOCS III e RMS IO x Log(s). Foi considerado como estatisticamente significante p≤ 0,05%. RESULTADOS: A média de idade dos pacientes foi de 72,3 anos (±8,9). As médias do PNS, do LOCS III, do Log(s) e da RMS IO, foram 2,7 (±1,14), 3,7 (±1,15), 1,49 (±0,38) e 1,23 (±0,5), respectivamente. As correlações de Spearman e o seu coeficiente de correlação (rho) foram p=0,270 (rho 0,20) entre Log(s) x PNS, um p=0,717 (rho 0,06) entre Log(s) x LOCS III, um p=0 (rho 0,76) entre LOCS III x PNS, um p=0,41 (rho -0,15) entre RMS IO x PNS, um p=0,39 (rho -0,15) entre RMS IO x LOCS III e um p=0,83 (rho 0.03) entre RMS IO x Log(s). CONCLUSÃO:A perda da qualidade de....

Purpose: To correlate straylight levels, lens scattering, lens opacity and intraocular aberrometry in patients with nuclear cataract. Methods: This is a prospective study. Thirty consecutive patients (30 eyes) were including. Ocular Straylight was evaluated using the C-Quant. Lens scattering was evaluated using Scheimpflug anterior segment tomography, using the new software PNS. Dilated slip lamp evaluation was performed and lens opacity was classified according to LOCS III scale. Total wavefront was measured by ray tracing (iTrace); intraocular aberrations were calculated by the integration of the Placido topography (Vista, Tracy Technologies. Exclusion criteria: corneal disease, retinal or optic nerves disease or previous ocular surgery. This is study analyzed was Kolmogorov-Smirnov for Normality. Spearman correlation test was performed. Results: The mean age from patients was 72,3 y (±8,9). The mean PNS was 2,7 (±1,14), the mean LOCS III was 3,7 (±1,15) and the mean Log(s) was 1,49(±0,38). The correlations between Log(s) x PNS, Log(s) x LOCS III and LOCS III x PNS obtained respectively p=0,270 (rho 0,20), p=0,717 (rho 0,06) e p=0 (rho 0,76). The mean RMS IO was 1,23 (+/- 0,5). The correlations between RMS IO x PNS was p=0, 41 (rho -0,15) and RMS IO x LOCS III was p=0,39 (rho -0.15) and between RMS IO x Log(s) was p=0,83 (rho 0,03). CONCLUSION: There is an association between the ...