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Rev Med Chil ; 135(5): 573-9, 2007 May.
Artigo em Espanhol | MEDLINE | ID: mdl-17657325

RESUMO

BACKGROUND: Drug-eluting stents have been developed to reduce the rates of restenosis after coronary angioplasty. Several studies have demonstrated that rapamycin eluting stents are reliable and effective. AIM: To report the experience in our Health Centre with rapamycin-eluting stents. PATIENTS AND METHODS: Forty two stents with rapamicine were implanted to 32 diabetic patients, between June 2002 and December 2004. After the procedure, subjects were clinically followed-up for an average period of 19.9+/-9.9 months, evaluating functional capacity, angina pectoris, dyspnea, need for hospital admission, acute coronary events and cardiac death. In those subjects clinically suspected to have restenosis, a coronary angiography was performed. RESULTS: Twenty-nine subjects (90.6%) remained asymptomatic, two subjects (6.3%) developed angina pectoris but restenosis was ruled out, and one subject (3.1%) died. CONCLUSIONS: The use of rapamycin-eluting stents in these patients was safe and successful with no evidence of clinic restenosis. These positive results are similar to those reported in the Diabetes Study.


Assuntos
Angioplastia , Estenose Coronária/terapia , Angiopatias Diabéticas/terapia , Stents Farmacológicos , Imunossupressores/uso terapêutico , Sirolimo/uso terapêutico , Distribuição de Qui-Quadrado , Reestenose Coronária/prevenção & controle , Diabetes Mellitus Tipo 2/terapia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Reprodutibilidade dos Testes , Resultado do Tratamento
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