[Formation of bone in critical calvarias defects in rats under the influence of bisphosphonate alendronate Na complex]. / Novoobrazovanie kostnoi tkani v kriticheskikh defektakh svoda cherepa krys pod vliyaniem kompleksa, soderzhashchego bisfosfonat alendronat natriya.

The aim of the study was to investigate dynamic of tissue structures in critical defects of calvaria of rats after inoculation of bisphosphonate (BF) alendronate Na complex into bone defects. Animal model included 24 Wistar rats divided in 3 groups: spontaneous healing under blot clot (1), inoculation of carbonate hydroxide apatite ß-tricalcium phosphate blocks (2) and BF alendronate Na complex (3) on 15, 30, 60 and 90 experiment day. New bone formation was observed in group 3 as opposed to groups 1 and 2.

[A comparative study of bone regeneration potency of alfa and beta-tricalcium phosphate bone substitute materials].

Review of the literature and our own investigations describe structure, synthesis and participation in biomineralisation of bone of synthetic bone scaffold tricalcium phosphate with original surface.