1.
Molecules
; 14(1): 19-35, 2008 Dec 23.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19104483
RESUMO
A series of etacrynic acid derivatives was synthesized and screened for their in vitro activity against Plasmodium falciparum, as well as their activity against recombinantly expressed falcipain-2 and -3. The two most active compounds of the series displayed IC(50) values of 9.0 and 18.8 microM against Plasmodia.