RESUMO
Results of the hemostasis conduction in conditions of revascularization in 106 patients, оperated on for atherosclerotic affection of aorta and the main arteries of the lower extremities, were adduced. Syndrome of hypercoagulation of traumatic stage of surgical intervention in early postoperative period is developing due to thrombinemia on background of a fibrinolytic system depression. There was proved a necessity to impact on thrombin-fibrinous factor (factor ÐÐа) of hemocoagulant cascade by application of nonfractionized heparins immediately after conclusion of operative intervention with thromboprophylaxis prolongation, using low-molecular heparins (impact on Ха factor) in accordance to the branch standards.
Assuntos
Arteriosclerose Obliterante/cirurgia , Artéria Femoral/cirurgia , Heparina/uso terapêutico , Neovascularização Fisiológica , Trombofilia/prevenção & controle , Procedimentos Cirúrgicos Vasculares/métodos , Anticoagulantes/uso terapêutico , Arteriosclerose Obliterante/sangue , Arteriosclerose Obliterante/patologia , Fator Xa/metabolismo , Artéria Femoral/patologia , Hemostasia/fisiologia , Humanos , Extremidade Inferior/irrigação sanguínea , Extremidade Inferior/patologia , Extremidade Inferior/cirurgia , Período Pós-Operatório , Protrombina/antagonistas & inibidores , Protrombina/metabolismo , Trombofilia/sangue , Trombofilia/patologia , Procedimentos Cirúrgicos Vasculares/instrumentaçãoAssuntos
Fibrinolíticos/uso terapêutico , Trombectomia/métodos , Terapia Trombolítica/métodos , Veia Cava Inferior/cirurgia , Trombose Venosa/tratamento farmacológico , Doença Aguda , Ablação por Cateter/instrumentação , Ablação por Cateter/métodos , Humanos , Trombectomia/instrumentação , Filtros de Veia Cava , Veia Cava Inferior/patologia , Trombose Venosa/sangue , Trombose Venosa/patologia , Trombose Venosa/cirurgiaRESUMO
In patients with chronic calculous cholecystitis, the number of T-lymphocytes decreased, the number of B-lymphocytes and their ability to transform into the blasts in response to stimulation of the specific bacterial antigen increased, the synthesis of immunoglobulins intensified, a titre of the antibodies specific to microflora of the biliary mucosa grew, the levels of complement, lysozyme and properdin decreased, the bacterial activity of blood serum was suppressed. It is necessary to correct these disorders in the process of preoperative preparation of the patients.
Assuntos
Reações Antígeno-Anticorpo/imunologia , Colecistite/imunologia , Colelitíase/imunologia , Adulto , Idoso , Formação de Anticorpos/imunologia , Doença Crônica , Humanos , Imunidade Celular/imunologia , Imunoglobulinas/análise , Contagem de Leucócitos , Pessoa de Meia-IdadeRESUMO
Sixty-two patients with acute cholecystitis and 108 patients with chronic calculous cholecystitis were examined. High levels of contamination of the bile, gallbladder mucosa and gallstones were shown. E. coli, Staphylococcus and Streptococcus were most frequent among 20 species of aerobic and anaerobic bacteria. Preoperative sanation of the hepatoduodenal area with antibiotics did not result in complete elimination of the bacteria in the bile, gallbladder mucosa and gallstones. The use of nitrofurans and especially furazolidone and furagin in the preoperative period prevented the microbial growth in the specimens collected during the operations. The data of the study allow recommending the use of furazolidone and furagin for preoperative sanation of the biliferous tract.
