[Irradiation doses of population in mountainous Adjara region of Georgia].

Radionuclide content of food and water in high mountainous regions of Georgia - Adjara (Keda, Shuakhevi, Khulo) has been studied, internal and total irradiation doses for the population have been defined and preventive measures for its reduction have been proposed. Internal irradiation dose for the population caused by K-40 was identified as 0,63 mSv/y, total irradiation dose - 1,73 mSv/y, that slightly exceeds acceptable levels, due to this it seems desirable to provide some measures with aim to reduce the radiation dose of the population and conduct further observation of the radiation situation. Measures intended to reduce irradiation doses includes: provision of population with less radioactive water sources, the regulation of medical radiation procedures (mostly - X-ray diagnostic procedures), the rational use of fertilizers with 40K content, construction of buildings on the territories with the lowest values of gamma radiation and radon release from soil, use of materials with low content of natural radionuclides for building construction, provision of premises with effective ventilation and radiation monitoring of buildings at any stages of construction, reconstruction or repair.

[Radioecological situation of Racha-Lechkhumi region of Georgia and hygienic assessment of external irradiation doses of population].

Radioecological situation in Racha-Lechkhumi region of Georgia (Ambrolauri, Oni, Lentekhi, Tsageri districts) and annual effective doses of external irradiation of population have been studied. It was found that outdoor radiation background in Racha-Lechkhumi region is 58.0-169.0 nGy/h; average index is 108.9 nGy/h. Indoor radiation background is 68.0-192.0 nGy/h; average index is 137.4 nGy/h. The average annual effective dose of external irradiation of population in Racha-Lechkhumi region is 0.81 mSv/y, which exceeds the dose of similar type registered in most of countries. The implementation of adequate preventive measures for its reduction is required.

[The radiation background and hygienic assessment of external irradiation doses of population in some mountainous regions of Georgia].

The radioecological situation of Mtskheta-Mtianeti region of Georgia has been studied. Doses from external irradiation were determined and estimated. The average value of radiation background (RB) of open areas in Mtskheta-Mtianeti region accounts 84.6 nGy/h, which is nearly equal to the average values in the countries of western Europe. This shows that investigated territories have high natural radiation background, which considering the geographical position and geophysical situation of Georgia is normal. The average value of radiation background of buildings in investigated territories accounts 120.4 nGy/h, which is little more than worldwide average value. The average annual dose from external irradiation (without radon component) for population of Mtskheta-Mtianeti region accounts 0.99 mZv/y, which is slightly more than worldwide average value. Since approximately 2/3 of effective equivalent dose comes from internal radiation and 1/3--from external radiation, it's reasonable to suppose that the radiation load of population of Mtskheta-Mtianeti region is significant and requires implementation of radiation dose reduction measures.

[Comparison of radiation background and frequency of genetic abnormalities among infants of Adjara foreland].

Radioecological situation of Adjara foreland and external irradiation doses of population have been studied. A comparison of frequency of genetic abnormalities (congenital abnormalities, underweight) among infants born in 2004-2008 and magnitude of the radiation background (RB) of region was studied to establish the causal connection between genetic abnormalities and RB. It was found, that relatively high dose of external irradiation is not the determining negative factor affecting the health of the newborns. At the same time, various factors of low intensity in nature, the magnitude of the RB and total irradiation dose contribute to the development of a congenital anomaly.

[Monitoring of the radioecological situation of Adjara seacoast].

One of the most important problems of the modern science is the study of biological, physiological and pathological influence of the radiation background on the surrounding environment. The disaster in the Chernobyl Atomic Power Station vitalized and sharpened the problem, as far as after the accident the Black Sea coast was exposed to the pollution. The Radiation background of Adjara seacoast has been studied in Georgia during the period of 1997 to 2002. The level of the radiation background in open areas lowered from 95 hgy/h to 93 hgy/h. The indicators of indoor radiation background have not been essentially changed--110 hgy/h. The average annual dose of irradiation of the population insignificantly lowered from 0,94 mZv/y to 0,937 mZv/y.

[Various indicators of the immune status of medical roentgenologists]. / Nekotorye pokazateli immunnogo statusa meditsinskikh rentgenologov.

Study of certain immune status indicators of medical roentgenologists has detected certain immunodeficiency associated with exposure to low doses of ionizing radiation. The number of T-lymphocytes has been noticed to be reduced, while the degree of reduction increases with age, duration of work in the sphere of radiation, and the value of the individual dose of radiation within a year. B-lymphocytes number is susceptible to changes in a smaller degree.

[Combined use of metronidazole and short-term hyperglycemia during radiation therapy of tumors in rats]. / Kombinirovannoe primenenie metronidazola i kratkovremennoi giperglikemii pri luchevoi terapii opukholei krys.

A simultaneous combined treatment with metronidazole and short-term hyperglycaemia, in contrast to application of each of these agents alone, enhanced considerably the therapeutic effect of radiation (a single and fractionated exposure). This was indicated by the increased rate of tumor regression, the number of animals with transient remission, and the number of cured animals which exhibited no relapse throughout the entire 90-day period of observation.

[Increase in the effectiveness of irradiating sarcoma-45 in rats using metronidazole]. / Povyshenie éffektivnosti oblucheniia sarkomy-45 krys metronidazolom.

A single exposure to ionizing radiation combined with the administration of metronidazole accelerated the regression of sarcoma-45 and increased the number of animals with fully regressed tumors as compared to control rats exposed to radiation alone. The maximum effect was registered when tumors were irradiated 90 min after the administration of metronidazole. With fractionated irradiation the radiosensitizing effect of metronidazole was less pronounced.