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1.
J Appl Clin Med Phys ; 17(1): 143-157, 2016 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-26894346

RESUMO

The purpose of this investigation was to evaluate the dose on megavoltage CT (MVCT) images required for tomotherapy. As imaging possibilities are often used before each treatment and usually used several times before the session, we tried to evaluate the dose delivered during the procedure. For each scanning mode (fine, normal, and coarse), we first established the relative variation of these doses according to different technical parameters (explored length, patient setup). These dose variations measured with the TomoPhant, also known as Cheese phantom, showed the expected variations (due to the variation of scattered radiation) of 15% according to the explored length and ± 5% according to the phantom setup (due to the variation of the point of measurement in the bore). In order to estimate patient doses, an anthropomorphic phantom was used for thermoluminescent and film dosimetry. The degree of agreement between the two methods was very satisfactory (the differences correspond to 5 mGy per imaging session) for the three sites studied (head & neck, thorax, and abdomen). These measurements allowed us to estimate the delivered dose of between 1 cGy and 4 cGy according to the site and imaging mode. Finally, we attempted to investigate a way to calculate this delivered dose in our patients from the study conducted on a cylindrical phantom and by taking into account data from the initial kV-CT scan. The results we obtained were close to our measurements, with discrepancies below 5 mGy per MVCT.


Assuntos
Neoplasias Abdominais/diagnóstico por imagem , Dosimetria Fotográfica/métodos , Neoplasias de Cabeça e Pescoço/diagnóstico por imagem , Imagens de Fantasmas , Radioterapia Guiada por Imagem/métodos , Neoplasias Torácicas/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos , Neoplasias Abdominais/radioterapia , Neoplasias de Cabeça e Pescoço/radioterapia , Humanos , Processamento de Imagem Assistida por Computador , Dosagem Radioterapêutica , Planejamento da Radioterapia Assistida por Computador , Radioterapia de Intensidade Modulada , Neoplasias Torácicas/radioterapia
2.
Phys Med Biol ; 60(5): 2103-6, 2015 Mar 07.
Artigo em Inglês | MEDLINE | ID: mdl-25675153

RESUMO

The purpose of this study was to investigate the suitability of a graphics library based model for the assessment of linear accelerator radiation leakage. Transmission through the shielding elements was evaluated using the build-up factor corrected exponential attenuation law and the contribution from the electron guide was estimated using the approximation of a linear isotropic radioactive source. Model parameters were estimated by a fitting series of thermoluminescent dosimeter leakage measurements, achieved up to 100 cm from the beam central axis along three directions. The distribution of leakage data at the patient plane reflected the architecture of the shielding elements. Thus, the maximum leakage dose was found under the collimator when only one jaw shielded the primary beam and was about 0.08% of the dose at isocentre. Overall, we observe that the main contributor to leakage dose according to our model was the electron beam guide. Concerning the discrepancies between the measurements used to calibrate the model and the calculations from the model, the average difference was about 7%. Finally, graphics library modelling is a readily and suitable way to estimate leakage dose distribution on a personal computer. Such data could be useful for dosimetric evaluations in late effect studies.


Assuntos
Elétrons , Modelos Teóricos , Aceleradores de Partículas/instrumentação , Dosimetria Termoluminescente/métodos , Humanos , Doses de Radiação
3.
Phys Med Biol ; 57(22): 7725-39, 2012 Nov 21.
Artigo em Inglês | MEDLINE | ID: mdl-23123826

RESUMO

Our purpose was to assess the out-of-field dose component related to head scatter radiation in high-energy photon therapy beams and then derive a multisource model for this dose component. For scattered photons, several planar sources have been defined, with number, location and tilt depending on the complexity of the field shape. In the absence of precise knowledge of out-of-field scattering characteristics, several assumptions are made to derive emission spectra and radiation intensity from measurements. Among these, the Compton formula is used to evaluate scattered photon energy and the Henyey-Greenstein phase function is used to evaluate the scattered photon angular distribution. For measured doses under out-of-field conditions, the average local difference between the calculated and measured photon dose is 10%, including doses as low as 0.01% of the maximum dose on the beam axis. This study demonstrates that the multi-plane source approach is suitable for accurate analytical modeling of the out-of-field dose component related to head scatter radiation. These results should be taken into account when evaluating doses to the remaining volume at risk in external beam radiotherapy planning.


Assuntos
Modelos Teóricos , Fótons/uso terapêutico , Doses de Radiação , Espalhamento de Radiação , Dosagem Radioterapêutica
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