Statistical Learning Signals for Complex Visual Images in Macaque Early Visual Cortex.

Animals of several species, including primates, learn the statistical regularities of their environment. In particular, they learn the temporal regularities that occur in streams of visual images. Previous human neuroimaging studies reported discrepant effects of such statistical learning, ranging from stronger occipito-temporal activations for sequences in which image order was fixed, compared with sequences of randomly ordered images, to weaker activations for fixed-order sequences compared with sequences that violated the learned order. Several single-unit studies in macaque monkeys reported that after statistical learning of temporal regularities, inferior temporal (IT) neurons show reduced responses to learned fixed-order sequences of visual images compared with random or mispredicted sequences. However, it is unknown how other macaque brain areas respond to such temporal statistical regularities. To address this gap, we exposed rhesus monkeys (Macaca mulatta) to two types of sequences of complex images. The "regular" sequences consisted of a continuous stream of quartets, and within each quartet, the image order was fixed. The quartets themselves were displayed, uninterrupted, in a random order. The same monkeys were exposed to sequences of other images having a pseudorandomized order ("random" sequence). After exposure, both monkeys were scanned with functional MRI (fMRI) using a block design with three conditions: regular sequence, random sequence, and fixation-only blocks. A whole-brain analysis showed a reduced activation in mainly the occipito-temporal cortex for the regular compared to the random sequences. Marked response reductions for the regular sequence were observed in early extrastriate visual cortical areas, including area V2, despite the use of rather complex images of animals. These data suggest that statistical learning signals are already present in early visual areas of monkeys, even for complex visual images. These monkey fMRI data are in line with recent human fMRI studies that showed a reduced activation in early visual areas for predicted compared with mispredicted complex images.

Simplification of Visual Rendering in Simulated Prosthetic Vision Facilitates Navigation.

Visual neuroprostheses are still limited and simulated prosthetic vision (SPV) is used to evaluate potential and forthcoming functionality of these implants. SPV has been used to evaluate the minimum requirement on visual neuroprosthetic characteristics to restore various functions such as reading, objects and face recognition, object grasping, etc. Some of these studies focused on obstacle avoidance but only a few investigated orientation or navigation abilities with prosthetic vision. The resolution of current arrays of electrodes is not sufficient to allow navigation tasks without additional processing of the visual input. In this study, we simulated a low resolution array (15 × 18 electrodes, similar to a forthcoming generation of arrays) and evaluated the navigation abilities restored when visual information was processed with various computer vision algorithms to enhance the visual rendering. Three main visual rendering strategies were compared to a control rendering in a wayfinding task within an unknown environment. The control rendering corresponded to a resizing of the original image onto the electrode array size, according to the average brightness of the pixels. In the first rendering strategy, vision distance was limited to 3, 6, or 9 m, respectively. In the second strategy, the rendering was not based on the brightness of the image pixels, but on the distance between the user and the elements in the field of view. In the last rendering strategy, only the edges of the environments were displayed, similar to a wireframe rendering. All the tested renderings, except the 3 m limitation of the viewing distance, improved navigation performance and decreased cognitive load. Interestingly, the distance-based and wireframe renderings also improved the cognitive mapping of the unknown environment. These results show that low resolution implants are usable for wayfinding if specific computer vision algorithms are used to select and display appropriate information regarding the environment.

Wayfinding with simulated prosthetic vision: performance comparison with regular and structure-enhanced renderings.

In this study, we used a simulation of upcoming low-resolution visual neuroprostheses to evaluate the benefit of embedded computer vision techniques in a wayfinding task. We showed that augmenting the classical phosphene rendering with the basic structure of the environment - displaying the ground plane with a different level of brightness - increased both wayfinding performance and cognitive mapping. In spite of the low resolution of current and upcoming visual implants, the improvement of these cognitive functions may already be possible with embedded artificial vision algorithms.