[Cytological examination of urethral and endocervical smears in the diagnosis of infections]. / Tsitologicheskoe issledovanie mazkov iz uretry i édotserviksa dlia diagnostiki infektsii.

Cytologic studies of smears from 130 women suffering from various diseases, including 61 pregnant patients with gestoses, have shown structural changes of the cells in the smears from the endocervix and urethra, that permitted the diagnosis of Mycoplasma infection in 43.8% of patients, Chlamydia infection, 52.3%, and herpes simplex in 72.3% of patients; in 63.9% of patients these infections were combined. Cytologic studies may be useful in the tentative diagnosis of urogenital infections, including cases when it is necessary to elucidate the causes of unfavorable course of a previous pregnancy or when preterm babies are born.

[The role of middle-weight molecules in the pathogenesis of late pregnancy toxemia]. / Rol' molekul srednei massy v patogeneze pozdnego toksikoza beremennykh.

Serum levels of plasma-derived toxic protein components, the median weight molecules (MWM), have been assayed in 206 women with third-trimester pregnancy and in their newborns. Toxemia of various severity was present in 194 women and had developed in the presence of an extragenital disease in 84.2% (pyelonephritis, glomerulonephritis, essential hypertension, etc.). Concentrations of MWM were found to increase with deterioration of renal function and to correlate with severity of nephropathy. In every second pregnancy with toxemia, interventions included extracorporeal detoxication: ultraviolet-irradiated blood autotransfusion (UIBA) and hemosorption. The rates of intra- and postpartum complications or requirement for surgery were 1.5-2-fold lower in these patients, and their newborns has better neonatal progress. Perinatal mortality of these patients was two times as low as that in the rest of the population (31.9:1000 versus 62.6:1000). The use of UIBA is recommended for mild and moderate toxemia and in combination with hemosorption for severe nephropathy.