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1.
Ann Thorac Surg ; 104(2): 599-605, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28242076

RESUMO

BACKGROUND: Stentless porcine extracellular matrix tricuspid tube grafts were developed for tricuspid valve reconstruction. The purpose of this study was to conduct an echocardiographic assessment of the performance of native and tube graft leaflets in an acute porcine model. METHODS: Fourteen 65-kg pigs were randomly assigned to tube graft (n = 7) or control with native valve preservation (n = 7). Epicardial echocardiography was performed at baseline after sternotomy, after valve operation, and after hemodynamic stabilization. RESULTS: No baseline differences were found (p > 0.05). All valves were competent with only a mild central regurgitant jet in two tube grafts and two native valves. Tube graft valves were compared with native valves. Anterior-septal leaflet coaptation length (18 ± 6 mm versus 6 ± 1 mm, p < 0.0005), coaptation height (20 ± 9 mm versus 9 ± 4 mm, p < 0.005), and anterior leaflet length (31 ± 1 mm versus 22 ± 2 mm, p < 0.00005) were all significantly larger in the tube graft valves. The billowing index (0.8 ± 0.1 versus 0.9 ± 0.1, p > 0.05) and tenting height (5 ± 1 mm versus 4 ± 2 mm, p > 0.1) were not significantly different. Leaflet excursion angles for both leaflets were not significantly different between the native and tube graft valves (p > 0.1). CONCLUSIONS: In a porcine experimental model, a competent tricuspid valve was constructed using extracellular matrix tube graft material. Coaptation geometry was significantly different from native valves with an increased coaptation zone because of excessive leaflet tissue in the tube graft valves. The tube graft tended to prolapse into the atrium, but it did not compromise the motion and competence of the leaflets.


Assuntos
Procedimentos Cirúrgicos Cardíacos/métodos , Doenças das Valvas Cardíacas/cirurgia , Próteses Valvulares Cardíacas , Procedimentos de Cirurgia Plástica/métodos , Engenharia Tecidual , Valva Tricúspide/cirurgia , Animais , Modelos Animais de Doenças , Ecocardiografia Transesofagiana , Doenças das Valvas Cardíacas/diagnóstico , Desenho de Prótese , Suínos , Valva Tricúspide/diagnóstico por imagem
2.
Ugeskr Laeger ; 176(5A): V07130460, 2014 Jan 27.
Artigo em Dinamarquês | MEDLINE | ID: mdl-25347341

RESUMO

Airway obstruction caused by massive subcutaneous emphysema (MSE) in the chest and neck region is a rare complication to tension pneumothorax. We describe the condition in a 91-year-old male in whom rapidly progressing MSE caused airway obstruction. As a result of progressing airway obstruction acute intubation was performed prior to completion of tube thoracostomy resulting in immediate improvement of the condition. This case demonstrates that MSE can lead to acute airway obstruction. Rapid intubation can in this situation be required to prevent asphyxiation.


Assuntos
Obstrução das Vias Respiratórias/etiologia , Enfisema Subcutâneo/complicações , Idoso de 80 Anos ou mais , Obstrução das Vias Respiratórias/terapia , Humanos , Intubação Intratraqueal , Masculino , Pneumotórax/complicações , Enfisema Subcutâneo/etiologia , Enfisema Subcutâneo/terapia
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