[T lymphocyte subpopulations in women with spontaneous abortions]. / Subpopulacije T limfocita u zena sa spontanim pobacajima.

Investigations were carried out to observe changes in the functional T-lymphocyte activity, as well as the presence of single T-lymphocyte subpopulations in the first trimester of pregnancy in 10 pregnant women with recurrent abortions in their previous pregnancies, compared to 8 healthy pregnant women in the first trimester and 20 of them in the third trimester of pregnancy, and in 30 healthy nonpregnant women at the fertile age. The functional T-lymphocyte activity (PHA-test) was decreased in pregnant women with recurrent abortions (54 +/- 0.99) and in healthy pregnant women (56 +/- 2.50) compared to healthy nonpregnant women (76 +/- 4.80). The total number of lymphocytes in the first trimester was decreased in the investigated group (22 +/- 5.38) and also in healthy pregnant women (25 +/- 1.55) in relation to nonpregnant women (33 +/- 3.15). The percentage of T-lymphocytes was similar (59 +/- 4.32 and 58 +/- 1.96 in relation to 80 +/- 2.80). Helper T-lymphocytes (T-4) were significantly decreased in the investigated group (28 +/- 4.25) compared to the group of healthy pregnant women in the first trimester (32 +/- 1.60) and healthy nonpregnant women (55 +/- 2.37). Suppression T-lymphocytes (T-8) were significantly increased in the investigated group (30 +/- 3.11) in relation to healthy pregnant women in the first trimester (25 +/- 2.45) and to healthy nonpregnant women (23 +/- 1.95). The ratio of helper T-lymphocytes and suppression T-lymphocytes (T4:T8) was significantly lower in pregnant women with recurrent abortions compared to healthy pregnant women in the first trimester and to healthy nonpregnant women.

[The effect of segmental epidural analgesia on the duration of labor in spastic dystocia]. / Utjecaj segmentalne epiduralne analgezije na trajanje porodaja sa spasticnom distocijom.

In 77 parturients, owing to spastic distotia, the labour was conducted in continuous epidural analgesia, while in the control group of parturients with the same diagnosis (N = 32), the intramuscular use of pethidine and diazepam was repeatedly applied. The epidural catheter was placed at the 2-3 cm dilated cervix. Carticain with or without fentanyl was used as a local anaesthetic. The average duration of labour from the beginning to the 2-3 cm cervical opening was 9.3 hours in the group of epidural analgesia applied parturients and 4.3 hours in the control group. The continuation of labor in the examined group lasted 3.7 hours and in the control group 12 hours. The difference is significant (p less than 0.01). A spontaneous vaginal delivery in the examined group was recorded in 77.9% women. There were 14.3% cesarean sections in the examined and 46.8% in the control group. A protracted labour was a significantly more frequent indication (p less than 0.01) for such a termination of labour in the control group.