SEOM clinical guideline of diagnosis and management of low-grade glioma (2017)

Diffuse infiltrating low-grade gliomas include oligodendrogliomas and astrocytomas, and account for about 5% of all primary brain tumors. Treatment strategies for these low-grade gliomas in adults have recently changed. The 2016 World Health Organization (WHO) classification has updated the definition of these tumors to include their molecular characterization, including the presence of isocitrate dehydrogenase (IDH) mutation and 1p/19p codeletion. In this new classification, the histologic subtype of grade II-mixed oligoastrocytoma has also been eliminated. The precise optimal management of patients with low-grade glioma after resection remains to be determined. The risk-benefit ratio of adjuvant treatment must be weighed for each individual (AU)

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SEOM clinical guideline of diagnosis and management of low-grade glioma (2017).

Diffuse infiltrating low-grade gliomas include oligodendrogliomas and astrocytomas, and account for about 5% of all primary brain tumors. Treatment strategies for these low-grade gliomas in adults have recently changed. The 2016 World Health Organization (WHO) classification has updated the definition of these tumors to include their molecular characterization, including the presence of isocitrate dehydrogenase (IDH) mutation and 1p/19p codeletion. In this new classification, the histologic subtype of grade II-mixed oligoastrocytoma has also been eliminated. The precise optimal management of patients with low-grade glioma after resection remains to be determined. The risk-benefit ratio of adjuvant treatment must be weighed for each individual.

Correction to: SEOM clinical guideline of diagnosis and management of low-grade glioma (2017).

The original version of this article unfortunately contained a mistake. Figure 3 was incorrect.

Resonancia magnética en el ependimoma anaplásico infratentorial pediátrico / Magnetic resonance imaging of infratentorial anaplastic ependymoma in children

Objetivo. El objetivo es mostrar las principales características radiológicas que el ependimoma anaplásico puede presentar en las imágenes de resonancia magnética (RM). Material y métodos. Se recogen los pacientes diagnosticados de ependimoma infratentorial de tipo anaplásico en los últimos 6 años en nuestro hospital terciario. Se estudian las características de imagen mediante RM (secuencias convencionales protocolizadas para estudio tumoral del SNC, difusión, estudio con contraste, espectroscopia) de este tipo tumoral. Resultados. El estudio de nuestra serie de 7 pacientes pediátricos con ependimoma anaplásico infratentorial no mostró características definitivas que ayudaran en la distinción entre grado II y grado III previamente al diagnóstico anatomopatológico, al no haber presentado ninguno de ellos diseminación al líquido cefalorraquídeo (LCR) en el momento del diagnóstico ni aumento de la restricción tumoral en la secuencia de difusión. Conclusiones. Las características radiológicas no son definitivas para distinguir entre los ependimomas grado II y los ependimomas anaplásicos grado III. Únicamente algunos detalles sobre la difusión y la mayor propensión a la diseminación al LCR, si se presentan, pueden diferenciarlos desde el punto de vista de la imagen (AU)

Objective. To show the main findings for anaplastic ependymoma on MRI. Material and methods. We reviewed all patients diagnosed with anaplastic ependymoma at our tertiary hospital during a six-year period. We recorded the MRI findings for this type of tumor (on conventional sequences following the protocol for the study of CNS tumors, diffusion-weighted imaging, contrast-enhanced sequences, and MR spectroscopy). Results. Our series comprises seven children with infratentorial anaplastic ependymoma. We found no definitive characteristics to distinguish between grade II and grade III tumors before histology, as none of the lesions had spread to the cerebrospinal fluid at diagnosis or showed increased restriction in the diffusion-weighted sequence. Conclusions. The MRI characteristics cannot definitively distinguish between grade II ependymomas and anaplastic grade III ependymomas. Only a few details about diffusion and dissemination to the cerebrospinal fluid, if present, can distinguish between these types at imaging (AU)

[Magnetic resonance imaging of infratentorial anaplastic ependymoma in children]. / Resonancia magnética en el ependimoma anaplásico infratentorial pediátrico.

OBJECTIVE: To show the main findings for anaplastic ependymoma on MRI. MATERIAL AND METHODS: We reviewed all patients diagnosed with anaplastic ependymoma at our tertiary hospital during a six-year period. We recorded the MRI findings for this type of tumor (on conventional sequences following the protocol for the study of CNS tumors, diffusion-weighted imaging, contrast-enhanced sequences, and MR spectroscopy). RESULTS: Our series comprises seven children with infratentorial anaplastic ependymoma. We found no definitive characteristics to distinguish between grade II and grade III tumors before histology, as none of the lesions had spread to the cerebrospinal fluid at diagnosis or showed increased restriction in the diffusion-weighted sequence. CONCLUSIONS: The MRI characteristics cannot definitively distinguish between grade II ependymomas and anaplastic grade III ependymomas. Only a few details about diffusion and dissemination to the cerebrospinal fluid, if present, can distinguish between these types at imaging.